Actively Recruiting
Registry Study for Optimal Management of Liver Failure in the Chinese Population
Led by First Affiliated Hospital Xi'an Jiaotong University · Updated on 2023-02-23
500
Participants Needed
14
Research Sites
312 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Liver failure is the most severe form of liver damage caused by viral, alcoholic, drug-related and ischemia-reperfusion factors, often combined with extrahepatic organ damage, resulting in a high mortality rate. This study intends to construct a real-world case registry database of inpatients with liver failure based on an electronic clinical data collection system through a multicenter collaborative network to study the clinical characteristics, epidemiology of bacterial and fungal infections, the impact of sarcopenia on clinical prognosis, and optimization of treatment strategies such as antiviral and artificial liver in Chinese inpatients with liver failure. The cohort and experience generated from this study will be used as a support for a series of future studies to focus on clinical issues such as infection, end-stage liver disease combined with organ failure, and early warning of critically ill patients.
CONDITIONS
Official Title
Registry Study for Optimal Management of Liver Failure in the Chinese Population
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosis consistent with liver failure or pre-liver failure
- Extreme weakness with significant gastrointestinal symptoms such as anorexia, vomiting, and abdominal distention
- Elevated alanine aminotransferase (ALT) and/or aspartate aminotransferase (AST) with progressive jaundice (total bilirubin ≥85.5 µmol/L)
- Bleeding tendency with prothrombin activity ≤60% or INR ≥1.5
You will not qualify if you...
- Any event or complication that significantly affects the assessment of clinical status according to the investigator
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 14 locations
1
First Affiliated Hospital of Xi'an Jiaotong University
Xi'an, Shaanxi, China, 710061
Actively Recruiting
2
Ankang Central Hospital
Ankang, China
Actively Recruiting
3
Xiangya Hospital of Central South University
Changsha, China
Not Yet Recruiting
4
Hanzhong 3201 Hospital
Hanzhong, China
Not Yet Recruiting
5
Qilu Hospital of Shandong University
Jinan, China
Not Yet Recruiting
6
First Hospital of Lanzhou University
Lanzhou, China
Not Yet Recruiting
7
Weinan Central Hospital
Weinan, China
Not Yet Recruiting
8
Air Force Medical University Tangdu Hospital
Xi'an, China
Not Yet Recruiting
9
Shaanxi provincial people's hospital
Xi'an, China
Not Yet Recruiting
10
The Second Affiliated Hospital of Xi'an Jiaotong University
Xi'an, China
Actively Recruiting
11
Xi 'an International Medical Center Hospital
Xi'an, China
Not Yet Recruiting
12
Xianyang Central Hospital
Xianyang, China
Actively Recruiting
13
The Affiliated Hospital of Yan'an University
Yanan, China
Not Yet Recruiting
14
General Hospital of Ningxia Medical University
Yinchuan, China
Not Yet Recruiting
Research Team
Y
Yingli He, Pro.
CONTACT
J
Juan Li, M.D.
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
3
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