Actively Recruiting
Registry Study on Patient Characteristics, Biological Disease Profile and Clinical Outcome in Acute Myeloid Leukemia and Related Neoplasms - The Biology and Outcome (BiO)-Project
Led by University of Ulm · Updated on 2026-01-05
50000
Participants Needed
94
Research Sites
1799 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This is a registry study in adult patients with newly diagnosed or refractory/relapsed myeloid neoplasms Investigator's sites: 80-90 sites in Germany and Austria Estimated duration of observation of an individual patient: 10 years maximum Objectives * To register all patients with AML and related neoplasms, newly diagnosed or relapsed/refractory in all AMLSG participating centers (completeness) * To perform rapid analyses of disease-related genetic markers (incidences, treatment recommendations) * To assess patient and family history, as well as patient characteristics * To evaluate treatment response (CR, CRh, CRi) and outcome data (event-free survival \[EFS\], relapse-free survival \[RFS\], cumulative incidence of relapse \[CIR\], cumulative incidence of death \[CID\], overall survival \[OS\]) * To evaluate the impact of measurable residual disease (MRD) by different methods * To assess biological disease features and correlate with clinical outcome data (prognostic and predictive markers) * To store biosamples from all patients (e.g., bone marrow, blood, plasma, normal tissue; e.g., skin biopsy, finger nails, hairs, sputum, or urine)
CONDITIONS
Official Title
Registry Study on Patient Characteristics, Biological Disease Profile and Clinical Outcome in Acute Myeloid Leukemia and Related Neoplasms - The Biology and Outcome (BiO)-Project
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients with suspected diagnosis of acute myeloid leukemia and related neoplasms, newly diagnosed or relapsed/refractory, classified according to the International Consensus Classification
- Age 218 years or older with no upper age limit
- Signed written informed consent
You will not qualify if you...
- Severe neurological or psychiatric disorder interfering with ability to give an informed consent
- No consent for registration, storage and processing of individual patient and disease data or informing the family physician about study participation
- No consent for biobanking of biological specimens and analyses on stored material
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 94 locations
1
Medizinische Universität Graz
Graz, Austria, 8036
Actively Recruiting
2
Medizinische Universität Innsbruck
Innsbruck, Austria, 6020
Actively Recruiting
3
Krankenhaus der Barmherzigen Schwestern Linz Betriebsgesellschaft m.b.H.
Linz, Austria, 4010
Suspended
4
Krankenhaus der Elisabethinen Linz GmbH
Linz, Austria, 4020
Actively Recruiting
5
Kepler Universitätsklinikum GmbH
Linz, Austria
Actively Recruiting
6
Landeskrankenhaus Feldkirch
Rankweil, Austria, 6807
Actively Recruiting
7
Universitätsklinikum der PMU Landeskrankenhaus Salzburg
Salzburg, Austria
Actively Recruiting
8
Hanuschkrankenhaus Wien
Vienna, Austria, 1140
Actively Recruiting
9
Klinikum Aschaffenburg
Aschaffenburg, Germany, 63739
Actively Recruiting
10
Klinikum Augsburg
Augsburg, Germany, 86156
Suspended
11
Ubbo-Emmius-Klinik Aurich
Aurich, Germany, 26603
Suspended
12
Helios Klinikum Bad Saarow
Bad Saarow, Germany, 15526
Actively Recruiting
13
Vivantes Klinikum am Urban
Berlin, Germany, 10967
Actively Recruiting
14
Vivantes Netzwerk für Gesundheit GmbH Klinikum Neukölln
Berlin, Germany, 12351
Actively Recruiting
15
Charité Universitätsmedizin Berlin Campus Virchow Klinikum
Berlin, Germany, 13353
Actively Recruiting
16
Helios Klinikum Emil von Behring
Berlin, Germany
Actively Recruiting
17
Vivantes Klinikum Spandau
Berlin, Germany
Actively Recruiting
18
Augusta-Kranken-Anstalt
Bochum, Germany, 44791
Actively Recruiting
19
Medizinische Universitätsklinik Knappschaftskrankenhaus Bochum
Bochum, Germany, 44892
Actively Recruiting
20
Universitätsklinikum Bonn
Bonn, Germany, 53105
Actively Recruiting
21
Städtisches Klinikum Braunschweig
Braunschweig, Germany, 38114
Actively Recruiting
22
Klinikum Bremen-Mitte gGmbH
Bremen, Germany, 28177
Actively Recruiting
23
Klinikum Darmstadt
Darmstadt, Germany, 64283
Actively Recruiting
24
St. Johannes Hospital
Dortmund, Germany, 44137
Actively Recruiting
25
Universitätsklinikum Düsseldorf
Düsseldorf, Germany, 40225
Actively Recruiting
26
Marien Hospital Düsseldorf GmbH
Düsseldorf, Germany
Actively Recruiting
27
Kliniken Essen-Süd Evang. Krankenhaus Essen-Werden gGmbH
Essen, Germany, 45239
Actively Recruiting
28
Klinikum Esslingen GmbH
Esslingen am Neckar, Germany, 73730
Actively Recruiting
29
St. Franziskus Hospital
Flensburg, Germany, 24939
Actively Recruiting
30
Städtische Kliniken Frankfurt am Main-Höchst
Frankfurt, Germany, 65929
Actively Recruiting
31
Medizinische Universitätsklinik
Freiburg im Breisgau, Germany, 79106
Actively Recruiting
32
MVZ Osthessen Medizinisches Versorgungszentrum
Fulda, Germany, 36043
Suspended
33
Klinik der Justus-Liebig-Universität
Giessen, Germany, 35385
Actively Recruiting
34
Wilhelm-Anton-Hospital gGmbH
Goch, Germany, 47574
Actively Recruiting
35
Alb Fils Kliniken GmbH
Göppingen, Germany, 73035
Actively Recruiting
36
Universitätsmedizin Göttingen
Göttingen, Germany, 37075
Actively Recruiting
37
Universitätsmedizin Greifswald
Greifswald, Germany
Actively Recruiting
38
Universitätsklinikum Hall
Halle, Germany
Actively Recruiting
39
Universitätsklinikum Hamburg-Eppendorf
Hamburg, Germany, 20246
Actively Recruiting
40
Asklepios Klinik Altona
Hamburg, Germany, 22763
Actively Recruiting
41
Asklepios Kliniken Hamburg GmbH St. Georg
Hamburg, Germany
Actively Recruiting
42
Evangelisches Krankenhaus Hamm
Hamm, Germany, 59063
Actively Recruiting
43
Klinikum Hanau gGmbH
Hanau, Germany, 63450
Actively Recruiting
44
Klinikum Hannover Siloah
Hanover, Germany, 30449
Actively Recruiting
45
Medizinische Hochschule Hannover
Hanover, Germany, 30625
Actively Recruiting
46
SLK-Kliniken Heilbronn GmbH
Heilbronn, Germany, 74078
Actively Recruiting
47
Marienhospital Herne Klinikum der Ruhr-Universität Bochum
Herne, Germany, 44625
Actively Recruiting
48
Universitätsklinikum des Saarlandes
Homburg/Saar, Germany, 66424
Actively Recruiting
49
Westpfalz-Klinikum Kaiserslautern
Kaiserslautern, Germany, 67655
Actively Recruiting
50
Städtisches Klinikum Karlsruhe
Karlsruhe, Germany, 76133
Actively Recruiting
51
St. Vincentius-Kliniken Karlsruhe
Karlsruhe, Germany, 76137
Actively Recruiting
52
Klinikum Kassel GmbH
Kassel, Germany, 34125
Active, Not Recruiting
53
Städtisches Krankenhaus Kiel GmbH
Kiel, Germany, 24116
Suspended
54
Helios Klinikum Krefeld
Krefeld, Germany
Actively Recruiting
55
Klinikum Landshut gGmbH
Landshut, Germany, 84034
Actively Recruiting
56
Caritas Krankenhaus Lebach
Lebach, Germany, 66822
Actively Recruiting
57
Klinikum Lippe-Lemgo
Lemgo, Germany, 32657
Actively Recruiting
58
Klinikum der Stadt Ludwigshafen am Rhein gGmbH
Ludwigshafen, Germany, 67063
Actively Recruiting
59
Universitätslinikum Schleswig-Holstein, Lübeck
Lübeck, Germany, 23538
Actively Recruiting
60
Klinikum Lüdenscheid
Lüdenscheid, Germany, 58515
Actively Recruiting
61
Univ-Klinikum der Otto-von-Guericke-Universität
Magdeburg, Germany, 39120
Actively Recruiting
62
Klinikum Magdeburg gGmbH
Magdeburg, Germany, 39130
Actively Recruiting
63
Universitätsklinikum der Johannes Gutenberg-Universität Mainz
Mainz, Germany, 55131
Actively Recruiting
64
Klinikum Hochsauerland GmbH
Meschede, Germany, 59872
Actively Recruiting
65
Johannes Wesling Klinikum Minden
Minden, Germany, 32429
Actively Recruiting
66
Klinikum Schwäbisch-Gmünd
Mutlangen, Germany, 73557
Actively Recruiting
67
Evangelisches Krankenhaus Mülheim an der Ruhr GmbH
Mühlheim, Germany, 45466
Actively Recruiting
68
Klinikum Schwabing
München, Germany, 80804
Suspended
69
Klinikum rechts der Isar der TU München
München, Germany, 81675
Actively Recruiting
70
Städtische Kliniken Neuss Lukaskrankenhaus GmbH
Neuss, Germany, 41464
Suspended
71
Sana Klinikum Offenbach
Offenbach, Germany, 63069
Actively Recruiting
72
Ortenau Klinikum, Offenburg-Gengenbach
Offenburg, Germany, 77654
Actively Recruiting
73
Pius Hospital Oldenburg
Oldenburg, Germany, 26121
Actively Recruiting
74
Klinikum Oldenburg gGmbH
Oldenburg, Germany, 26133
Actively Recruiting
75
Klinikum Passau
Passau, Germany, 94032
Actively Recruiting
76
Ernst-von-Bergmann-Klinikum Potsdam gGmbH
Potsdam, Germany, 14467
Actively Recruiting
77
Klinikum Vest
Recklinghausen, Germany, 45657
Actively Recruiting
78
Universitätsklinikum
Regensburg, Germany, 93053
Actively Recruiting
79
University hospital Rostock
Rostock, Germany
Actively Recruiting
80
Akademisches Lehrkrankenhaus des Saarlandes St. Theresia
Saarbrücken, Germany, 66113
Actively Recruiting
81
Marienhaus Klinikum St. Elisaeth Saarlouis
Saarlouis, Germany
Actively Recruiting
82
Nordwest-Krankenhaus Sanderbusch
Sande, Germany
Actively Recruiting
83
Klinikum Stuttgart Katharinenhospital
Stuttgart, Germany, 70174
Actively Recruiting
84
Diakonie-Klinikum Stuttgart
Stuttgart, Germany, 70176
Actively Recruiting
85
Vinzenz von Paul Kliniken gGmbH Marienhospital Stuttgart
Stuttgart, Germany, 70199
Actively Recruiting
86
Klinikum Traunstein
Traunstein, Germany, 83278
Actively Recruiting
87
Klinikum Mutterhaus der Borromäerinnen gGmbH
Trier, Germany, 54290
Actively Recruiting
88
Krankenhaus der Barmherzigen Brüder Trier
Trier, Germany, 54292
Actively Recruiting
89
Medizinische Universitätsklinik Tübingen
Tübingen, Germany, 72076
Actively Recruiting
90
University Hospital of Ulm
Ulm, Germany, 89081
Actively Recruiting
91
Universitätsklinik Ulm Labor für Zytogenetische und Molekulare Diagnostik
Ulm, Germany, 89081
Actively Recruiting
92
Schwarzwald-Baar Klinikum Villingen-Schwenningen GmbH
Villingen-Schwenningen, Germany, 78052
Actively Recruiting
93
Harzklinikum Dorothea Christiane Erxleben
Wernigerode, Germany, 38855
Actively Recruiting
94
Helios Klinikum Wuppertal
Wuppertal, Germany, 42283
Actively Recruiting
Research Team
H
Hartmut Döhner, Prof. Dr.
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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