Actively Recruiting

Age: 18Years - 99Years
All Genders
NCT03924817

Registry Study on Prescription, Patient Pathways, Therapy Efficacy and Usage of Mandibular Advancement Devices in Obstructive Sleep Apnea - PATT-OSA Registry

Led by ResMed · Updated on 2024-10-29

500

Participants Needed

4

Research Sites

73 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

During sleep, the muscle tonus in the oropharyngeal space is lost, the tongue might fall back andthe volume of the pharynx decreases. Air cannot pass through as it would in the awake state and thus airflow limitations occur. The person asleep might compensate the flow limitation by breathing faster, which causes the soft tissue to vibrate (= snoring). Further narrowing of the airways can lead to obstructive apneas (complete airway collapse and stopping of airflow). First line therapy for obstructive sleep apnea (OSA) is positive airway pressure (PAP) that keeps the airways open with a pneumatic splint. Since PAP involves wearing a facial mask that applies air pressure into the airways, some patients cannot tolerate this therapy. These patients might be candidates for an alternative treatment approach with a mandibular advancement device (MAD).

CONDITIONS

Official Title

Registry Study on Prescription, Patient Pathways, Therapy Efficacy and Usage of Mandibular Advancement Devices in Obstructive Sleep Apnea - PATT-OSA Registry

Who Can Participate

Age: 18Years - 99Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Prescription of any mandibular advancement device
  • Age �3E= 18 years
  • Ability to understand the study information and information on usage of personal data
  • Signed and dated informed consent
Not Eligible

You will not qualify if you...

  • Patients with central sleep apnea (central AI > 5/hour)
  • Patients with loose teeth and severe parodontitis
  • Patients with completely missing teeth or removable tooth replacement, or with a teeth health insufficient to retain an MAD
  • Patients with missing molars
  • Patients with maximum protrusion of less than 5mm

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 4 locations

1

Schlaf- und Beatmungszentrum Blaubeuren

Blaubeuren Abbey, Badden-Württemberg, Germany, 89143

Not Yet Recruiting

2

Ruhrlandklinik Essen

Essen, North Rhine-Westphalia, Germany, 45239

Actively Recruiting

3

Zentrum für Schlafmedizin Dr. Warmuth

Berlin, Germany, 12683

Not Yet Recruiting

4

Universitätsklinikum Regensburg - Klinik für Innere Medizin II

Regensburg, Germany, 93053

Not Yet Recruiting

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Research Team

O

Oliver Munt, PhD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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