Actively Recruiting
Regression of Cervical Precancerous Lesions and Associated Risk Factors
Led by General University Hospital, Prague · Updated on 2026-02-25
300
Participants Needed
1
Research Sites
252 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The aim of this study is to assess the extent of histopathological regression of severe cervical precancerous lesions (CIN 2 and CIN 3); evaluate the proportion of patients who experience the normalization of HPV test and cytology finding among those who were treated conservatively and those who underwent conization; and identify predictive parameters associated with regression. Based on this analysis, a model will be proposed to predict the likelihood of lesion regression.
CONDITIONS
Official Title
Regression of Cervical Precancerous Lesions and Associated Risk Factors
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Squamocolumnar junction fully visualized
- Biopsy-confirmed diagnosis of CIN 2 or CIN 3
- Age 18 years or older
- Age 40 years or younger
- Provided informed consent
You will not qualify if you...
- Squamocolumnar junction not fully visualized
- Suspicion of glandular lesion
- Suspicion of invasive cancer
- Personal history of CIN 2, CIN 3, or cervical cancer
- Currently pregnant
- HIV positive
- Immunosuppressed
- Unable to obtain photographic documentation
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
General University Hospital
Prague, Czechia, 12800
Actively Recruiting
Research Team
L
Lukas Dostalek
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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