Actively Recruiting
Rehabilitation of Airway Protection in Parkinson's Disease
Led by Teachers College, Columbia University · Updated on 2025-09-24
120
Participants Needed
2
Research Sites
263 weeks
Total Duration
On this page
Sponsors
T
Teachers College, Columbia University
Lead Sponsor
N
National Institute of Neurological Disorders and Stroke (NINDS)
Collaborating Sponsor
AI-Summary
What this Trial Is About
Airway protective disorders are a prevalent and progressive consequence of Parkinson's Disease (PD), and often result in aspiration pneumonia which is the leading cause of death in PD. Despite this, a large number of patients with PD do not access specialized services to address these critical deficits. The investigators will examine the comparative effectiveness of a novel treatment paradigm delivered in-person versus via telehealth in persons with PD, as well as the role of patient burden and treatment adherence on outcomes; thus, the proposed research is relevant to public health and in line with NIH's mission to identify novel, efficacious, and accessible rehabilitation strategies for short- and long-term improvement of dysfunctional airway protection in PD.
CONDITIONS
Official Title
Rehabilitation of Airway Protection in Parkinson's Disease
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosed with Parkinson's Disease at Hoehn and Yahr Stages II-IV confirmed by a Movement Disorders specialist using strict UK brain bank criteria
- Presence of airway protective deficits shown by penetration of thin liquids or reduced cough strength
- Not currently receiving exercise-based swallowing therapy
- Aged between 50 and 90 years
You will not qualify if you...
- Other neurological disorders such as multiple sclerosis, stroke, or brain tumor
- History of head and neck cancer
- History of breathing disorders like COPD
- Smoking history in the last five years
- Uncontrolled hypertension
- Severe neuropsychological dysfunction including severe depression or dementia
- Allergy to capsaicin or barium
- Living more than 1.5 hours away from either Teachers College, Columbia University or Purdue University
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 2 locations
1
Purdue University
West Lafayette, Indiana, United States, 47907
Actively Recruiting
2
Teachers College, Columbia University
New York, New York, United States, 10027
Active, Not Recruiting
Research Team
M
Michelle Troche, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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