Actively Recruiting

Phase 3
Age: 40Years - 90Years
All Genders
NCT06488144

Rehabilitation for Arthritis of The Knee: mainTaining Improvement for Veterans

Led by VA Office of Research and Development · Updated on 2026-01-08

254

Participants Needed

5

Research Sites

211 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The aims are to determine whether 1) an incentive based on behaviorally-enhanced gamification and social incentives and 2) health coaching can promote adherence to exercise and physical activity after physical therapy for osteoarthritis of the knee (KOA). The research design is a randomized clinical trial with factorial design This randomized clinical trial of 254 patients using a factorial design will leverage a clinical trial platform developed through the University of Pennsylvania that allows for the remotely capture important patient-reported outcomes and other interaction through a participant's smart phone. The investigators will randomize participants to receive social incentives with gamification to promote adherence to prescribed exercises as well as maintenance of greater levels of physical activity and compare to controls that receive a Fitbit but no additional incentive. Participants may also be randomized to receive a health coach. The investigators will utilize mobile applications for smart phones and wearable activity trackers through the Way-to-Health platform and assess, in real time, the impact of the interventions on patient-reported function and pain (as measured by the Knee Osteoarthritis Outcome Score) as well as physical activity. Participants will be followed for 2 years, with a total of 5 in-person visits. Knee osteoarthritis (KOA) is one of the most prevalent and disabling conditions among Veterans and accounts for high morbidity and high costs for the VA. Importantly, while physical therapy is valuable for patients with KOA, lack of adherence to home exercises and low overall physical activity limit the durability of response. The current proposal aims to address two important knowledge gaps in the management of KOA in order to improve pain and function.

CONDITIONS

Official Title

Rehabilitation for Arthritis of The Knee: mainTaining Improvement for Veterans

Who Can Participate

Age: 40Years - 90Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Clinical diagnosis of chronic knee osteoarthritis
  • Age between 40 and 90 years
  • Starting physical therapy for knee osteoarthritis within the next month or had first PT visit within the last 7 days
  • Physical therapist agrees you can safely and reliably participate in ongoing exercise
  • Completed at least 4 virtual or in-person physical therapy appointments
  • Able to sync your Fitbit at least once a month
Not Eligible

You will not qualify if you...

  • No smartphone to use the Way-to-Health platform
  • Unable to walk 2 blocks without help
  • Poorly controlled crystalline arthritis or other inflammatory arthritis
  • Life expectancy less than 1 year as determined by provider
  • Severe heart failure, unstable angina, end stage kidney disease, severe lung disease, or other serious illness limiting exercise or posing safety risk
  • Severe pain in a non-knee area that limits daily function
  • Non-English speakers or limited reading ability that prevents use of text messages
  • Pregnancy
  • Receiving physical therapy outside the VA

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Trial Site Locations

Total: 5 locations

1

Birmingham VA Medical Center, Birmingham, AL

Birmingham, Alabama, United States, 35233-1927

Not Yet Recruiting

2

Omaha VA Nebraska-Western Iowa Health Care System, Omaha, NE

Omaha, Nebraska, United States, 68105-1850

Not Yet Recruiting

3

VA Portland Health Care System, Portland, OR

Portland, Oregon, United States, 97207-2964

Not Yet Recruiting

4

Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA

Philadelphia, Pennsylvania, United States, 19104-4551

Actively Recruiting

5

VA Puget Sound Health Care System Seattle Division, Seattle, WA

Seattle, Washington, United States, 98108-1532

Not Yet Recruiting

Loading map...

Research Team

J

Joshua F Baker, MD MSCE

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

FACTORIAL

Primary Purpose

TREATMENT

Number of Arms

4

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here