Actively Recruiting

Phase Not Applicable
Age: 18Years - 80Years
All Genders
NCT06802159

Rehabilitation Methods for Unilateral Spatial Neglect in Stroke Patients

Led by Federal Center of Cerebrovascular Pathology and Stroke, Russian Federation Ministry of Health · Updated on 2025-06-22

30

Participants Needed

2

Research Sites

48 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Stroke remains one of the leading causes of mortality and disability worldwide. Between 30% and 40% of patients who have had an acute cerebral hemorrhage, develop unilateral spatial neglect syndrome (USN). USN is observed in 24% of patients with left-hemispheric stroke and 45% of patients with right-hemispheric lesions in the acute phase acute phase and in 20% of patients in the chronic phase. The presence of USN significantly complicates the rehabilitation process and negatively affects the functional outcomes. The complexity of USN correction is due to the heterogeneity of its manifestations and combination with other cognitive disorders. In 30-50% of patients with USN anosognosia is observed, in 60% - memory and attention disorders. Traditional methods of rehabilitation lead to significant improvement in 30-50% of patients with USN. The use of combined methods of treatment, including pharmacotherapy and non-medication methods, can improve efficacy by up to 70-80%. This indicates the need to develop and investigate new approaches to correct USN. Despite the growing number of studies in this area, there is still no unified approach to selecting the optimal method of USN correction for each individual patient. Different methods of rehabilitation may have different effects on neuroplasticity processes, which opens new perspectives for optimization of rehabilitation strategies.

CONDITIONS

Official Title

Rehabilitation Methods for Unilateral Spatial Neglect in Stroke Patients

Who Can Participate

Age: 18Years - 80Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Normal cognitive development according to age and education level
  • Diagnosis with ICD codes I63 or I61
  • Presence of unilateral spatial neglect syndrome in neuropsychological assessment
Not Eligible

You will not qualify if you...

  • Severe or uncontrolled mental or physical illnesses
  • Significant eye movement disorders
  • Moderate to severe sensory visual defects

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

Federal Center of Brain and Neurotechnologies of the FMBA of Russia

Moscow, Moscow, Russia, 117997

Actively Recruiting

2

Federal Center of Brain and Neurotechnologies of the FMBA of Russia

Moscow, Russia, 117997

Actively Recruiting

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Research Team

S

Salima Eneeva

CONTACT

M

Marina Alekseevna, Dr

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

NON_RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

3

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