Actively Recruiting

Age: 16Years - 100Years
All Genders
NCT07093125

Rehabilitation Practices in Critically Ill Patients Receiving Invasive Mechanical Ventilation in the Intensive Care Unit.

Led by Universita degli Studi di Genova · Updated on 2026-05-04

2400

Participants Needed

1

Research Sites

208 weeks

Total Duration

On this page

Sponsors

U

Universita degli Studi di Genova

Lead Sponsor

A

Amsterdam UMC, location VUmc

Collaborating Sponsor

AI-Summary

What this Trial Is About

This international, multicenter, observational study aims to describe rehabilitation practices in Intensive Care Units (ICUs) worldwide. The primary objective is to provide an overview of current rehabilitation strategies used in ICUs globally. Secondary objectives include assessing the relationship between rehabilitation and key ICU outcomes such as ICU and hospital mortality, length of stay, duration of invasive ventilation, extubation failures, and long-term outcomes including quality of life and functional performance 28 days post-ICU discharge. The study will also compare rehabilitation practices across different geographic and economic regions to identify potential disparities. The study is structured into three modules, with participation contingent on local resources and feasibility. The BASIC Module (mandatory for all centers) gathers fundamental data on rehabilitation practices and their association with patient outcomes. The EXTENDED Module (optional) collects more detailed information on the type, timing, duration, and safety of rehabilitation interventions, including passive exercises, active mobilization, respiratory therapies, dysphagia training, occupational therapy, and cognitive support. The EXTENDED FOLLOW-UP Module (optional) evaluates the patient's quality of life and functional recovery 28 days after ICU discharge. By examining global rehabilitation practices and their impact on patient outcomes, this study aims to improve rehabilitation strategies in ICUs, contributing to better patient care, recovery, and long-term health outcomes.

CONDITIONS

Official Title

Rehabilitation Practices in Critically Ill Patients Receiving Invasive Mechanical Ventilation in the Intensive Care Unit.

Who Can Participate

Age: 16Years - 100Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients admitted to a participating ICU
  • Adult patients aged 16 years or older according to local regulations
  • Patients who have received invasive ventilation for at least 48 hours
  • Written informed consent obtained from the patient or next of kin as required by local laws
Not Eligible

You will not qualify if you...

  • Patients admitted for withdrawal of life-sustaining therapy

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

IRCCS Ospedale Policlinico San Martino

Genova, Italy, Italy, 16132

Actively Recruiting

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Research Team

D

Denise Battaglini, MD, PhD

CONTACT

M

Marcus J Schultz, MD, PhD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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