Actively Recruiting
Rehabilitation in Safety-net Environments (RISE) to Improve Outcomes in Vulnerable Patients With COPD
Led by University of California, San Francisco · Updated on 2025-12-01
387
Participants Needed
3
Research Sites
231 weeks
Total Duration
On this page
Sponsors
U
University of California, San Francisco
Lead Sponsor
N
National Heart, Lung, and Blood Institute (NHLBI)
Collaborating Sponsor
AI-Summary
What this Trial Is About
Chronic obstructive pulmonary disease (COPD), one of the leading causes of death in the US, disproportionately affects low socioeconomic communities. While few interventions effectively modify the course of COPD and improve outcomes, pulmonary rehabilitation is the one notable exception. However, implementation of this resource-intensive program in real-life settings, and in particular, for underserved communities, has proven to be challenging. Safety-net centers that serve primarily under-insured populations lack financial resources to provide pulmonary rehabilitation. The 10-week COPD Wellness and Plus+ Program directly addresses this gap, and yet, programs like these do not automatically lead to improved outcomes, which leads to the implementation of a Health Advocates program to address participant's social needs and barriers to healthcare.
CONDITIONS
Official Title
Rehabilitation in Safety-net Environments (RISE) to Improve Outcomes in Vulnerable Patients With COPD
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Signed and dated informed consent form
- Willingness to participate in the COPD Wellness program
- Age between 40 and 90 years
- English or Spanish speaking
- Physician-diagnosed COPD
- Spirometry-confirmed FEV1/FVC ratio �3C= 0.7 and FEV1% predicted �3C 80% based on GLI-O prediction
- COPD Assessment Test score �3E= 10 or history of exacerbations needing hospitalization or steroid therapy
- Currently prescribed COPD medication(s)
- Ability to exercise with lower extremities
- No COPD exacerbations for at least 6 weeks
- Currently receiving care within San Francisco Health Network (SFHN)
You will not qualify if you...
- Pregnancy
- Dementia, cognitive impairment, or psychiatric illness impairing participation
- Unstable cardiovascular disease including recent (less than 6 months) heart attack or pulmonary embolism, uncontrolled arrhythmia, poorly controlled heart failure
- Severe co-morbidities contraindicating exercise
- Transmittable pulmonary infections such as tuberculosis or COVID-19
- Participation in pulmonary rehabilitation within past 12 months
- COPD exacerbation in past 6 weeks
- Activity restrictions limiting moderate physical activity
- Other diagnosis or condition with prognosis of death within one year
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 3 locations
1
Zuckerberg San Francisco General (ZSFG) Hospital
San Francisco, California, United States, 94110
Actively Recruiting
2
Maxine Hall Health Center (MHHC)
San Francisco, California, United States, 94115
Actively Recruiting
3
Southeast Health Center (SEHC)
San Francisco, California, United States, 94124
Actively Recruiting
Research Team
N
Neeta Thakur, MD, MPH
CONTACT
V
Valeria M Rojas, BS
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
HEALTH_SERVICES_RESEARCH
Number of Arms
3
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here