Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06547827

Rehabilitation With and Without Robot and Allied Digital Technologies in Stroke Patients

Led by Fondazione Don Carlo Gnocchi Onlus · Updated on 2025-02-12

596

Participants Needed

13

Research Sites

102 weeks

Total Duration

On this page

Sponsors

F

Fondazione Don Carlo Gnocchi Onlus

Lead Sponsor

I

Istituti Clinici Scientifici Maugeri SpA

Collaborating Sponsor

AI-Summary

What this Trial Is About

Rehabilitation after stroke often employs Robot and Allied Digital Technologies (RADTs), yet evidence on their effectiveness remains inconclusive due to study heterogeneity and limited sample sizes. This multicentre randomized controlled pragmatic trial aims at comprehensively and accurately assessing the effectiveness of rehabilitation mediated by RADTs after a stroke, compared to traditional rehabilitation, also considering economic sustainability.

CONDITIONS

Official Title

Rehabilitation With and Without Robot and Allied Digital Technologies in Stroke Patients

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • First-ever diagnosis of ischemic or haemorrhagic stroke confirmed by CT or MRI
  • Age 18 years and over
  • Stroke occurred within 6 months prior to enrollment
  • Mild to severe impairment of upper limb (Fugl-Meyer Assessment motor section  58) and/or lower limb (Functional Ambulation Categories scale  4) and/or balance (Berg Balance Scale  45)
  • Clinically stable to allow transfer to gym and perform treatments
Not Eligible

You will not qualify if you...

  • Clinical instability
  • Severe cognitive or behavioral disorders preventing compliance (Montreal Cognitive Assessment <10)
  • Rigidity or hypertonia (Modified Ashworth Scale > 3) in affected limb
  • Serious uncorrectable visual impairments preventing use of technological or robotic devices
  • Pregnant women
  • Refusal to sign informed consent

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 13 locations

1

Fondazione Don Carlo Gnocchi, Centro Gala

Acerenza, Italy

Actively Recruiting

2

IRCCS Istituti Clinici Scientifici Maugeri

Bari, Italy

Not Yet Recruiting

3

IRCCS Ospedale Policlinico San Martino,

Genova, Italy

Actively Recruiting

4

Fondazione Don Carlo Gnocchi, IRCCS Santa Maria Nascente

Milan, Italy

Not Yet Recruiting

5

IRCCS Istituti Clinici Scientifici Maugeri

Milan, Italy

Not Yet Recruiting

6

IRCCS Istituti Clinici Scientifici Maugeri

Montescano, Italy

Actively Recruiting

7

IRCCS Fondazione Mondino

Pavia, Italy

Actively Recruiting

8

IRCCS Istituti Clinici Scientifici Maugeri

Pavia, Italy

Actively Recruiting

9

Fondazione Don Carlo Gnocchi, Centro Santa Maria della Provvidenza

Roma, Italy

Actively Recruiting

10

Fondazione Don Carlo Gnocchi, Centro Santa Maria al Mare

Salerno, Italy

Not Yet Recruiting

11

Fondazione Don Carlo Gnocchi, Polo Specialistico Riabilitativo

Sant'Angelo dei Lombardi, Italy

Actively Recruiting

12

IRCCS Istituti Clinici Scientifici Maugeri

Telese Terme, Italy

Not Yet Recruiting

13

Fondazione Don Carlo Gnocchi, Polo specialistico riabilitativo

Tricarico, Italy

Actively Recruiting

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Research Team

I

Irene G Aprile, MD, PhD

CONTACT

M

Marco Germanotta, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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