Actively Recruiting
The Relationship Between Brain MRI Phenotypes, Genes and Cognitive Outcome in CHD Adults
Led by Boston Children's Hospital · Updated on 2023-08-15
225
Participants Needed
1
Research Sites
204 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The main purpose of this proposal is to perform novel MRI analyses to determine the brain organizational changes associated with altered executive function and the modulating role of variants in neuroresilience and hypoxia response genes in adults with d-transposition of the great arteries (d-TGA).
CONDITIONS
Official Title
The Relationship Between Brain MRI Phenotypes, Genes and Cognitive Outcome in CHD Adults
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Participants who took part in the Boston circulatory arrest, pH and Hematocrit studies at Boston Children's Hospital as children
- Normally-developed young adults matched by age and sex
- Able to provide informed consent
- Willing to undergo brain MRI and limited neuropsychological testing including IQ assessment
You will not qualify if you...
- For control participants: unable to complete MRI due to implanted metal, claustrophobia, mental illness history, brain injury, or prior brain intervention
- Intellectual impairment preventing independent completion of study questionnaires
- Unable to speak and read English fluently
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Boston Children's Hospital
Boston, Massachusetts, United States, 02115
Actively Recruiting
Research Team
M
Michelle Gurvitz, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
OTHER
Number of Arms
1
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