Actively Recruiting
The Relationship Between Finger Ratio and Development in Infants
Led by Nigde Omer Halisdemir University · Updated on 2026-05-08
80
Participants Needed
1
Research Sites
51 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
One of the most prominent indicators of prenatal androgen exposure is considered to be the ratio of second and fourth finger lengths (2D:4D). The 2D:4D finger ratio refers to the ratio of the length of the second finger (2D; index finger) and the fourth finger (4D; ring finger). Evidence suggests that 2D:4D is developmentally stable and stabilizes from the second trimester of pregnancy. It has been reported that the 2D:4D ratio correlates positively with estrogen and negatively with testosterone. In both sexes, prenatal testosterone levels are inversely related by a 2D:4D ratio, which does not change with age. Androgens can have direct trophic effects on target cells or indirectly affect neuronal growth through neurotrophic mediators released locally by steroid-sensitive neuronal or glial cells. Prenatal testosterone can have long-term organizational effects on the structure and function of various body systems (e.g., cardiovascular and musculoskeletal systems) that are important for physical activity and exercise.
CONDITIONS
Official Title
The Relationship Between Finger Ratio and Development in Infants
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Term infants (37-40 weeks)
- Infants aged 12-18 months
You will not qualify if you...
- Preterm infants
- Infants with congenital infections or proven genetic changes
- Infants and mothers diagnosed with metabolic, neurological, and genetic diseases
- Maternal diabetes
- Intrauterine growth retardation
- Infants with a history of hand-related surgery
- Children whose parents did not volunteer to study
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Nigde Omer Halisdemir University
Niğde, Turkey (Türkiye)
Actively Recruiting
Research Team
R
Rabia ZORLULAR
CONTACT
R
Rabia Zorlular
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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