Actively Recruiting
Relationship Between Glycemic Control and Irisin in Type 2 Diabetic Patients With Sarcopenic or Non-sarcopenic Obesity
Led by Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari · Updated on 2024-08-01
120
Participants Needed
1
Research Sites
104 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this observational study is to compare glycemic control and irisin levels in subjects with diabetes mellitus type 2 with sarcopenic obesity vs non-sarcopenic obesity. The main questions it aims to answer are: Is glycemic control worse in diabetic patients with sarcopenic obesity? Are irisin levels higher in patients with non-sarcopenic obesity? Participants will be asked to: * Fill in three questionaries on lifestyle * Perform two physical performance tests The investigators will collect the following data: * Anthropometric measurements * Body composition by bioelectrical impedance analysis. * Results of routine blood analyses * Irisin levels by drawing a vial of blood from the antecubital vein
CONDITIONS
Official Title
Relationship Between Glycemic Control and Irisin in Type 2 Diabetic Patients With Sarcopenic or Non-sarcopenic Obesity
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diabetes mellitus type 2 diagnosed less than 10 years before
- Age over 60 years
- Body Mass Index (BMI) over 30 kg/m2
- Estimated Glomerular Filtration Rate (eGFR) above 30 ml/min
- On stable antidiabetic therapy for at least 3 months
You will not qualify if you...
- Use of insulin or insulin secretagogues
- Diagnosis of type 1 diabetes or history of diabetic ketoacidosis
- Neuromuscular diseases
- Endocrine disorders causing muscle disease (e.g., hypercortisolism, growth hormone deficiency, acromegaly, adrenal insufficiency, hypopituitarism, male hypogonadism, hyperparathyroidism, hypoparathyroidism)
- Severe vitamin D deficiency (less than 12 ng/ml)
- Blood disorders (hemoglobinopathies)
- Prolonged immobilization
- Conditions causing fluid retention (severe heart failure NYHA class III/IV, severe kidney or liver failure)
- Active cancers within the past 5 years
- Severe arthritis of the knee or hip
- Having a pacemaker
AI-Screening
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Trial Site Locations
Total: 1 location
1
Policlinico di Bari
Bari, Italy, 70124
Actively Recruiting
Research Team
F
Francesco Giorgino, MD, PhD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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