Actively Recruiting
Relationship Between LS Chirp ABR and Speech-in-Noise Skills in Hidden Hearing Loss
Led by Istanbul University - Cerrahpasa · Updated on 2025-11-17
63
Participants Needed
1
Research Sites
40 weeks
Total Duration
On this page
Sponsors
I
Istanbul University - Cerrahpasa
Lead Sponsor
M
Medipol University
Collaborating Sponsor
AI-Summary
What this Trial Is About
It is known that the underlying problem in Hidden Hearing Loss (HHL) is cochlear synaptopathy (CS) and that low-spontaneous-rate auditory nerve fibers play an important role in this pathology. Therefore, it is suggested that low-spontaneous-rate auditory nerve fibers are damaged in HHL. Consequently, LS CE-Chirp-evoked ABR and HINT, which assesses CS by presenting stimuli of varying intensities and characteristics to provide information about auditory nerve fibers, will be used to evaluate participants both objectively and subjectively. Aim of the study: The main aim of this study is to investigate the relationship between the amplitude and latency values obtained with LS CE-Chirp-stimulated ABR and the critical Signal-to-Noise Ratio (SNR) obtained from the Hearing in Noise Test (HINT) in individuals suspected of having HHL. Hypotheses H0: In individuals suspected of having HHL, there is no relationship between the amplitude values of waves I, III, and V obtained with LS CE-Chirp ABR at 80, 90, and 100 dBnHL and the I/V amplitude ratio and the critical SNR obtained from HINT. H1: In individuals suspected of having HHL, there is a relationship between the amplitude values of waves I, III, and V obtained with LS CE-Chirp ABR at 80, 90, and 100 dBnHL and the I/V amplitude ratio, and the critical SNR obtained from HINT. Expected Results: The study will reveal how LS CE-Chirp stimulation affects ABR results in individuals suspected of having HHL, and the relationship between these results and HINT results will be examined. In this way, HHL will be evaluated both objectively (LS CE-Chirp ABR) and subjectively (HINT). Based on the findings, scientific outputs such as publications or projects are targeted. Importance: HHL has recently attracted increasing attention as a condition that significantly affects daily life. In today's world, where noise and noisy environments are prevalent, disadvantages arise in many aspects, particularly in communication. Therefore, the findings obtained in this study may contribute to a better understanding of HHL.
CONDITIONS
Official Title
Relationship Between LS Chirp ABR and Speech-in-Noise Skills in Hidden Hearing Loss
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Aged between 20 and 60 years
- Bilateral pure-tone audiometry averages (500-1000-2000-4000 Hz) within normal range (≤25 dB HL)
- No tinnitus or auditory complaints (control group)
- Chronic tinnitus complaint lasting 3 months or more (first study group)
- No chronic tinnitus complaint and low score on Speech Perception subscale of SSQ (second study group)
- Score 21 or above on the Montreal Cognitive Assessment (MoCA) test
- No emotional or neurological problems that could interfere with tests
You will not qualify if you...
- Presence of peripheral and/or central hearing loss
- Presence of somatosensory tinnitus
- Presence of emotional and/or neurological problems that could interfere with tests
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Istanbul University-Cerrahpaşa
Istanbul, Turkey (Türkiye)
Actively Recruiting
Research Team
C
Cem Yeral, MSc
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
3
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