Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT05921695

The Relationship Between Normal Saline Infusion and Acute Kidney Injury in Heat Stroke

Led by Second Affiliated Hospital, School of Medicine, Zhejiang University · Updated on 2024-09-20

190

Participants Needed

7

Research Sites

144 weeks

Total Duration

On this page

Sponsors

S

Second Affiliated Hospital, School of Medicine, Zhejiang University

Lead Sponsor

Y

Yiwu Central Hospital

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goal of this clinical trial is to compare the effect of high chlorine solution such as normal saline and non-high chlorine solution such as sodium lactate ringer's solution on renal function in patients with heat stroke. The main question it aims to answer is whether limiting the amount of normal saline infusion during emergency department can lower the incidence of acute kidney injury and mortality in patients with heat stroke. Participants will receive a free normal saline infusion during the emergency department according to the study design, or a restricted normal saline infusion while using sodium lactate Ringer's instead. Researchers will compare the normal saline infusion group and sodium lactate Ringer's group to see if limiting the amount of normal saline infusion during emergency department can lower the incidence of acute kidney injury and mortality in patients with heat stroke.

CONDITIONS

Official Title

The Relationship Between Normal Saline Infusion and Acute Kidney Injury in Heat Stroke

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • 18 years or older
  • Diagnosed with heat stroke
  • Provided informed consent or consent from family members
Not Eligible

You will not qualify if you...

  • Need immediate cardiopulmonary resuscitation
  • Transferred from another hospital
  • Have original end-stage renal disease or require dialysis
  • Have severe organ damage
  • Are pregnant

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 7 locations

1

YongKang First People's Hospital

Guli, Zhejiang, China, 321300

Actively Recruiting

2

Yiwu Central Hospital

Yiwu, Zhejiang, China

Actively Recruiting

3

Dongyang People's Hospital

Dongyang, China

Actively Recruiting

4

The Second Affiliated Hospital of Zhejiang University School of Medicine

Hangzhou, China, 310000

Actively Recruiting

5

Jinhua Municipal Central Hospital

Jinhua, China

Actively Recruiting

6

Jinhua People's Hospital

Jinhua, China

Actively Recruiting

7

Lanxi People's Hospital

Lanxi, China

Actively Recruiting

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Research Team

X

Xiuqin Feng, PRO

CONTACT

L

Lan Chen, PHD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

CROSSOVER

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

2

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The Relationship Between Normal Saline Infusion and Acute Kidney Injury in Heat Stroke | DecenTrialz