Actively Recruiting
The Relationship Between Preoperative Frailty and Postoperative AKI and the Mediating Effect of Intraoperative BP
Led by Lanyue Zhu · Updated on 2026-04-02
1000
Participants Needed
1
Research Sites
78 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The primary objectives of study is to compare the difference in the incidence of postoperative AKI between frail and non-frail patients. The secondary objectives of study was to compare the differences in intraoperative blood pressure fluctuations, the incidence and duration of intraoperative hypotension, postoperative extubation time, postoperative complications, length of hospital stay and hospitalization expenses between frail and non-frail patients, and use mediating effect analysis to examine the magnitude of the effect of intraoperative blood pressure on postoperative acute kidney injury caused by frailty.
CONDITIONS
Official Title
The Relationship Between Preoperative Frailty and Postoperative AKI and the Mediating Effect of Intraoperative BP
Who Can Participate
Eligibility Criteria
You may qualify if you...
- 18 years old or above
- Undergo non-cardiac surgery
You will not qualify if you...
- Missing at least one serum creatinine measurement before or after surgery
- End-stage renal disease with dialysis within the past year
- Baseline serum creatinine greater than or equal to 4.5 mg/dl
- Acute kidney injury within 7 days before surgery
- No frailty assessment conducted
- Undergoing renal surgery
- Operation time less than 2 hours
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Zhongda Hospital Southeast University
Nanjing, Jiangsu, China, 210000
Actively Recruiting
Research Team
Y
Yue Lan Zhu
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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