Actively Recruiting

Age: 18Years - 80Years
All Genders
NCT06786169

The Relationship of Psychological Stress With Therapy Efficacy and Prognosis of Gastric Cancer

Led by Fudan University · Updated on 2025-01-22

600

Participants Needed

1

Research Sites

262 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This is the prospective, observational cohort study (G-Distress) to explore the associations of psychological stress with treatment and prognosis of gastric cancer. The participants including the patients diagnosed with gastric cancer who received surgery, chemotherapy and immune checkpoint inhibitors.

CONDITIONS

Official Title

The Relationship of Psychological Stress With Therapy Efficacy and Prognosis of Gastric Cancer

Who Can Participate

Age: 18Years - 80Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age between 18 and 80 years with ECOG performance status 0 or 1
  • Diagnosed primary adenocarcinoma of gastric cancer or gastroesophageal junction cancer confirmed by pathology
  • Cohort 1: Stage II-III disease, having R0 gastrectomy with D2 lymphadenectomy, receiving adjuvant chemotherapy
  • Cohort 2: Stage III-IV disease, scheduled for gastrectomy and preoperative chemotherapy
  • Cohort 3: Stage IV disease, not eligible for gastrectomy, with at least one measurable lesion per RECIST 1.1
Not Eligible

You will not qualify if you...

  • History of prior chemotherapy, radiotherapy, immunotherapy, or targeted therapy (Cohort 1)
  • Multiple primary tumors
  • Serious other diseases including cardiovascular, respiratory, kidney, or liver disease, or poorly controlled hypertension, diabetes, or mental disorders
  • Unable to undergo R0 resection and D2 lymph node dissection (Cohort 1)
  • Patients with stage IV gastric cancer (Cohort 1)
  • Unable to receive chemotherapy, radiotherapy, immunotherapy, or targeted therapy (Cohorts 2 and 3)
  • Unable to undergo gastrectomy when required (Cohort 2)

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Fudan University Shanghai Cancer Center

Shanghai, Shanghai Municipality, China, 200000

Actively Recruiting

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Research Team

J

Jing Guo, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

3

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