Association between lactic acidosis and multiple organ dysfunction syndrome after cardiopulmonary bypass.
Dan Zheng, Guo-Liang Yu, Yi-Ping Zhou...
https://pubmed.ncbi.nlm.nih.gov/38313014Actively Recruiting
Led by Hôpital Armand Trousseau · Updated on 2025-05-01
500
Participants Needed
1
Research Sites
N/A
Total Duration
Researchers are studying whether the amount of veinous lactate measured at the end of surgery is linked to complications within 3 months after surgery in infants aged 0 to 1 year. This observational study focuses on young children undergoing surgery under general anesthesia, excluding those having day-case or cardiac surgery. The goal is to see if higher lactate levels could predict post-operative problems in this age group, similar to findings in adults. The study involves infants under 1 year old who undergo non-cardiac surgery with general anesthesia. Blood samples for lactate measurement are taken routinely before the child wakes up from anesthesia, using the intravenous line placed for anesthesia. The investigation centers on routine surgical procedures without additional experimental treatments. During the study, infants' blood lactate levels are measured at the end of surgery, and researchers monitor for any complications occurring within 3 months after surgery. Data collection includes routine blood sampling from the anesthesia IV line. The main outcome is the occurrence of post-operative complications during the follow-up period. Participation duration covers the surgery day plus 3 months of monitoring for any complications.
CONDITIONS
Relevance of Veinous Lactates to Predict Postoperative Complications in Children 0-1 Years
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Complete this quick 3-step screening to check your eligibility
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - Day of surgery
Participants undergo surgery under general anesthesia and immediate post-operative care.
1 visit (in-person)
Duration - Up to 3 months after surgery
Participants are monitored for post-operative complications after surgery.
Regular follow-up visits during this period
Total: 1 location
1
Armand Trousseau University Hospital
Paris, France, 75012
Actively Recruiting
M
Mireille Nasr, MD
N
Nada Sabourdin, MD, PhD
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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Dan Zheng, Guo-Liang Yu, Yi-Ping Zhou...
https://pubmed.ncbi.nlm.nih.gov/38313014Elizabeth H Stephens, Conrad L Epting, Carl L Backer...
https://pubmed.ncbi.nlm.nih.gov/32294015