Actively Recruiting
RELIEF OF PSYCHOEMOTIONAL STRESS USING XENON SEDATION
Led by The S.N. Fyodorov Eye Microsurgery State Institution · Updated on 2025-06-27
140
Participants Needed
1
Research Sites
126 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this clinical trial is to propose for implementation and evaluate the effectiveness of xenon sedation for the relief of psychoemotional stress disorder before the operation of refractive laser vision correction patients with high anxiety and stress instability who underwent xenon analgosedation before refractive laser vision correction. The main question\[s\] it aims to answer are: 1. To develop a method of xenon sedation in patients with a high level of psychoemotional stress before surgery - refractive laser vision correction. 2. To evaluate the effect of inhaled xenon anesthesia in a sub-narcotic dose on the duration of surgery, satisfaction of surgeons and patients with anesthesia, the level of postoperative pain in patients in comparison with anxiolytics. The following will be studied: the level of preoperative anxiety, the dynamics of glycemia and blood cortisol levels, heart rate variability, electrical microamplitudes of the ECG signal, the anti-stress and analgesic effect of xenon. If there is a comparison group: the researchers will compare \[the group with xenon sedation and the control group\] to see if there is \[an anti-stress effect of xenon in patients before laser vision correction\].
CONDITIONS
Official Title
RELIEF OF PSYCHOEMOTIONAL STRESS USING XENON SEDATION
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Upcoming operation ReLEx4 SMILE
- High anxiety and stress instability with a Spielberger-Khanin test score of 46 points or more
- Signed informed consent to participate in the study
You will not qualify if you...
- Concomitant somatic diseases in the decompensation stage
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
s. Fyodorov Eye Microsurgery Federal State Inctitution
Krasnodar, Russia, 350012
Actively Recruiting
Research Team
A
Alexandr Romanov
CONTACT
V
Viktoria Myasnikova
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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