Actively Recruiting

Phase Not Applicable
Age: 18Years - 65Years
All Genders
NCT04694534

Remediation Program Via a "Serious Game" for the Cognitive Functions of Multiple Sclerosis Patients

Led by Lille Catholic University · Updated on 2025-09-04

150

Participants Needed

6

Research Sites

281 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The main goal of this study is to assess the effectiveness of a cognitive remediation program based on a "serious game" on the information processing speed evolution and the process of learning via episodic memory in multiple sclerosis patients.

CONDITIONS

Official Title

Remediation Program Via a "Serious Game" for the Cognitive Functions of Multiple Sclerosis Patients

Who Can Participate

Age: 18Years - 65Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosed with relapsing-remitting or progressive multiple sclerosis based on Mc Donald's 2005 criteria
  • Aged between 18 and 65 years old
  • Have cognitive complaints with at least one deficient neuropsychological test score (below 5th percentile), including at least one BICAMS test score
  • No relapse within the last 6 weeks
  • At least 4 weeks since last corticosteroid bolus
  • Not receiving neuroleptic treatment
  • Have internet access
  • Signed informed consent form
Not Eligible

You will not qualify if you...

  • Severe cognitive deficit with deficits in more than six cognitive processes
  • Receiving neuropsychological care
  • Unable to understand or receive oral and written information
  • Unable to use the study software due to motor or sensory difficulties
  • Neurological or psychiatric conditions other than multiple sclerosis or anxiodepressive syndrome
  • Severe anxiodepressive syndrome (BDI score above 27)
  • Participating in another interventional study on cognitive functions
  • Under legal protection, guardianship, or curatorship
  • Pregnant or breastfeeding women

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 6 locations

1

CH Arras

Arras, Hauts-de-France, France, 62000

Actively Recruiting

2

CH LENS

Lens, Hauts-de-France, France, 62300

Actively Recruiting

3

CHRU

Lille, Hauts-de-France, France, 59000

Actively Recruiting

4

Saint Vincent hospital

Lille, Hauts-de-France, France, 59000

Actively Recruiting

5

Saint-Philibert hospital

Lomme, Nord, France, 59462

Actively Recruiting

6

Charles Nicolle Hospital

Rouen, Normandy, France, 76000

Actively Recruiting

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Research Team

A

Amélie Lausiaux, MD, PhD

CONTACT

E

Elodie Moutailler

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

DIAGNOSTIC

Number of Arms

2

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