Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT05298150

Remote Dynamic Cycling for the Customized Off-site Rehab in Parkinson's Disease

Led by VA Office of Research and Development · Updated on 2026-01-07

72

Participants Needed

1

Research Sites

208 weeks

Total Duration

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AI-Summary

What this Trial Is About

This research will develop novel and accessible way to deliver effective and customized rehab to those suffering from common and devastating neurodegenerative condition called Parkinson's disease. The investigators will examine the efficacy of novel rehab technique that can be monitored and modified in real-time but over virtual interface using a remotely located device in a paradigm called dynamic cycling. This technology will benefit thousands of Veterans who need customized and cost-effective rehab but cannot travel to specialized facilities due to inevitable limitations such as pandemics or because of lack of resources, social support, frailty, or home-bound status.

CONDITIONS

Official Title

Remote Dynamic Cycling for the Customized Off-site Rehab in Parkinson's Disease

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosis of Parkinson's disease using the UK Brain Bank criteria
  • Ability to perform informed consent
  • Hoehn and Yahr stages I to III when off medication
  • Stable antiparkinsonian medication regimen for at least six months
Not Eligible

You will not qualify if you...

  • Montreal Cognitive Assessment score less than 18
  • Hamilton depression score of 20 or higher
  • Hamilton anxiety rating score greater than 24
  • Clinical diagnosis of perinatal brain injury, stroke, or atypical parkinsonism
  • Signs or symptoms of untreated cardiovascular disease including chest pain, shortness of breath, dizziness, orthopnea, ankle edema, palpitations, intermittent claudication, heart murmur, or unusual fatigue with usual activity

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Louis Stokes VA Medical Center, Cleveland, OH

Cleveland, Ohio, United States, 44106-1702

Actively Recruiting

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Research Team

A

Aasef G Shaikh, MD PhD

CONTACT

V

Varun Sundaram, MBBS PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

TRIPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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