Actively Recruiting
Remote Ischemic Conditioning Plus Stenting for Symptomatic Carotid Artery Stenosis
Led by General Hospital of Shenyang Military Region · Updated on 2026-04-03
300
Participants Needed
1
Research Sites
90 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Remote ischemic conditioning (RIC) has emerged as a promising non-invasive strategy to protect the brain, with evidence suggesting its benefit in patients with carotid artery stenting (CAS). However, the long-term benefit and safety of chronic RIC in this population remain unknown. This trial aims to evaluate whether chronic RIC reduces the incidence of major vascular events and improves clinical outcomes in high-risk patients with carotid artery stenosis who received CAS.
CONDITIONS
Official Title
Remote Ischemic Conditioning Plus Stenting for Symptomatic Carotid Artery Stenosis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 6 40 years old
- Symptomatic moderate to severe stenosis of the internal carotid artery
- History of ipsilateral cerebral ischemic symptoms within the past 180 days
- Planned for carotid artery stent
- Essen Score 6 3
- Modified Rankin Scale score of 0 or 1
- Signed informed consent
You will not qualify if you...
- Uncontrolled severe hypertension (systolic > 180 mmHg or diastolic > 110 mmHg despite medication)
- Subclavian artery stenosis 6 50% or presence of subclavian steal syndrome
- Severe hematological disorders or significant coagulation abnormalities
- Contraindications to remote ischemic conditioning, such as severe soft tissue injury, fracture, or vascular injury in the upper limbs, or peripheral vascular disease in the distal upper limbs
- Severe comorbid conditions with a life expectancy of less than 1 year
- Participation in another clinical trial within the past 3 months or ongoing participation
- Any other circumstances deemed by the investigator as unsuitable for participation in this clinical study
AI-Screening
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Trial Site Locations
Total: 1 location
1
Department of Neurology, General Hospital of Northern Theater Command
Shenyang, China, 110016
Actively Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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