Actively Recruiting
Remote Ischemic Conditioning for PwSCI
Led by Washington University School of Medicine · Updated on 2026-03-23
24
Participants Needed
1
Research Sites
74 weeks
Total Duration
On this page
Sponsors
W
Washington University School of Medicine
Lead Sponsor
T
The Craig H. Neilsen Foundation
Collaborating Sponsor
AI-Summary
What this Trial Is About
The long-term goal of this project is to improve the overall cardiometabolic health of persons with spinal cord injury (SCI). This pilot study will test the feasibility and acceptability of remote ischemic conditioning implemented in a home setting by persons with SCI and collect cardiometabolic health outcomes to inform appropriate outcomes for a future larger trial. Researchers will compare, RIC high dose using standard blood pressure cuff to RIC high dose using automated blood flow restriction cuff to RIC low dose using standard blood pressure cuff, to determine cardiometabolic health improvements amongst groups. Participants will: Complete an initial 2-day assessment, participate in a 6-week intervention using remote ischemic conditioning (RIC) within their home, complete a 2-day post assessment.
CONDITIONS
Official Title
Remote Ischemic Conditioning for PwSCI
Who Can Participate
Eligibility Criteria
You may qualify if you...
- 18 years of age or older
- Diagnosis of spinal cord injury (SCI)
- Living in the community (not in a nursing facility)
- Not currently engaging in physical activity for exercise
- Unable to participate in physical activity due to physical or environmental barriers
- Medically stable
- Ability to obtain physician approval to participate
- Willingness to attend a 2-day initial assessment and a 2-day post-intervention assessment
- Willingness to complete 30 remote ischemic conditioning sessions independently or with caregiver assistance
You will not qualify if you...
- Medically unstable
- Heart-related condition within the past year
- Blood clot within the past year
- Stage 3 or 4 pressure injury
- Use of blood thinners in the past year
- Surgery within the past year
- Uncontrolled hypertension
- Peripheral artery disease
- Complex Regional Pain Syndrome (CRPS) in both arms
- Nerve or tendon transfers in the arms within the past year
- Lymphedema in the arms
- Recent acute illness or injury within the past 3 months
- Currently pregnant
- Enrolled in another clinical trial
- Taking GLP-1 medications
- Unable to provide consent
- Currently engaged in physical activity for exercise
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Washington University School of Medicine
St Louis, Missouri, United States, 63108
Actively Recruiting
Research Team
K
Kerri A Morgan, PhD
CONTACT
W
Walker
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
BASIC_SCIENCE
Number of Arms
3
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