Actively Recruiting

Age: 18Years +
FEMALE
NCT06818760

Remote Monitoring in Pregnant Women With Congenital Heart Disease Using Wrist Wearables

Led by The Cleveland Clinic · Updated on 2026-02-13

50

Participants Needed

1

Research Sites

204 weeks

Total Duration

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AI-Summary

What this Trial Is About

Congenital heart disease (CHD) includes a wide variety of types of disease, including congenital abnormalities of the heart valves. This can range from bicuspid aortic valve and other aortic valve deformities to more complex disease such as tetralogy of Fallot. For many kinds of CHD, the optimal timing of interventions remains unclear. For instance, in tetralogy of Fallot, there is still equipoise about when to offer pulmonary valve replacement (PVR), while in aortic regurgitation, some patients can remain stable for many years. The primary focus of this study is to use continuous physiologic data (CPD), obtained using wearable biosensors (a type of biometric monitoring technology), to develop improved biomarkers of disease progression and prognosis from patients with congenital heart disease (CHD) who are pregnant while they are at home as well as looking at patients' experience and interaction with wearable biosensor technology at home.

CONDITIONS

Official Title

Remote Monitoring in Pregnant Women With Congenital Heart Disease Using Wrist Wearables

Who Can Participate

Age: 18Years +
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Women evaluated in the cardio-obstetrics clinic either prepartum, intrapartum, or postpartum with congenital heart disease.
  • Congenital heart disease based on modified World Health Organization (mWHO) classification group 6 II or higher.
  • Includes specific mWHO classes: II, II-III, III, and IV with detailed heart conditions as described.
  • Congenital valvular heart disease with moderate or greater regurgitation or stenosis by echocardiography.
  • Bioprosthetic valvular heart disease with moderate or greater regurgitation or stenosis.
  • Any mechanical valve prosthesis.
  • Congenital cardiomyopathy with ejection fraction less than 50%.
  • Provide informed consent.
  • Age 18 years or older.
Not Eligible

You will not qualify if you...

  • Patients on hemodialysis.

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Cleveland Clinic

Cleveland, Ohio, United States, 44195

Actively Recruiting

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Research Team

J

Joanna Ghobrial, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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