Actively Recruiting
Remote vs. In-Person Study Evaluation (RISE) Trials: RISE Above Smoking (Trial 1)
Led by State University of New York at Buffalo · Updated on 2026-04-15
200
Participants Needed
2
Research Sites
102 weeks
Total Duration
On this page
Sponsors
S
State University of New York at Buffalo
Lead Sponsor
M
Medical University of South Carolina
Collaborating Sponsor
AI-Summary
What this Trial Is About
The study will employ a randomized, parallel-group design with two-stage randomization. After an initial brief screen for basic eligibility, participants will be randomized (within site) to either Remote (R) or In-Person (IP) Intake Groups. During the Intake, detailed consent and eligibility assessment will be completed. Participants who are eligible at the Intake will be randomized (within site and Intake Group) to R or IP Treatment and Assessment Groups. Participants will be followed for 3 months.
CONDITIONS
Official Title
Remote vs. In-Person Study Evaluation (RISE) Trials: RISE Above Smoking (Trial 1)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years or older
- Stable mailing address within 1.5 hours of a study site
- Ability to read, speak, and understand English
- Own an iOS or Android smartphone
- Have a valid email address checked regularly or regular access to text messages
- Daily cigarette smoker of 5 or more cigarettes per day for at least 6 months
- Moderate or greater motivation to quit smoking (score of 6 or higher on Motivation to Stop Smoking Scale)
- Agree to refrain from other tobacco products and non-study cessation treatments during the trial
- Willing to be randomized to attend remote or in-person visits
You will not qualify if you...
- Use of tobacco or nicotine products other than cigarettes (except blunts, spliffs, cigars, little cigars, cigarillos) for 5 or more days per week over the past 3 months
- Allergy or intolerance to nicotine replacement therapy patch or lozenge
- Pregnant, breastfeeding, or planning to become pregnant within 4 months
- Use of varenicline, nicotine replacement therapy, or bupropion in the past 7 days to quit smoking
- Consumption of more than 28 alcoholic drinks per week
- High-risk involvement with illicit or nonmedical prescription drugs (score 27 or higher on NIDA-modified ASSIST)
- Suicide attempt with some wish to die in the past 3 months
- Recent hospitalization due to mental illness such as schizophrenia, bipolar disorder, or major depression within the past 30 days
- Unable or unwilling to provide informed consent or follow directions, or inappropriate responses observed by staff
- For participants aged 21 or older: refusal to provide or show a pack of cigarettes for documentation at intake
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
University at Buffalo
Buffalo, New York, United States, 14260
Actively Recruiting
2
University of Pennsylvania
Philadelphia, Pennsylvania, United States, 19104
Actively Recruiting
Research Team
L
Larry W Hawk, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
OTHER
Number of Arms
4
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here