Home-Based Brain Stimulation and Cognitive Training to Improve Attention in Active Duty Service Members and Veterans with Mild Traumatic Brain Injury

What this Trial Is About

Researchers are evaluating a new way to help improve complex attention in Active Duty Service Members and Veterans who have experienced mild traumatic brain injury mTBI. This study tests a home-based, non-invasive brain stimulation method called Remotely Supervised Transcranial Direct Current Stimulation combined with Cognitive Training RS-tDCS. The goal is to boost cognitive training effects by enhancing brain learning and reorganization. The study also examines brain changes using EEG and MRI scans and looks at how factors like PTSD, depression, and sleep quality affect outcomes. Participants will be randomly assigned to receive either active RS-tDCS or a sham placebo version along with cognitive training exercises. They will complete 10 sessions over two weeks at home, with stimulation applied for 20 minutes per session via electrodes on a special headband. Cognitive training involves five computer-based exercises targeting executive functions such as working memory and decision making, adapted to each participants ability. After the intervention, participants are assessed again at one week and six weeks to measure lasting effects. During the study, participants will undergo tests of attention and symptoms along with brain imaging at baseline and post-intervention. Daily assessments of symptoms, cognition, and mood will be collected during and after treatment through momentary surveys. Researchers will monitor safety through symptom questionnaires and track quality of life changes. The entire participation lasts several weeks, including treatment and follow-up assessments to evaluate both immediate and lasting impacts of the intervention.

Remotely Supervised tDCS+ for Complex Attention in mTBI (Cognetric)