Actively Recruiting

Age: 18Years - 50Years
All Genders
NCT06631404

Renal Arterial Resistive Index as a Noninvasive Biomarker of Disease Activity in Lupus Nephritis Patients

Led by Sohag University · Updated on 2024-10-08

55

Participants Needed

1

Research Sites

56 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Systemic Lupus Erthymatosous (SLE) is achronic inflammatory multi system auto immue disease characterized by pathogenic auto anti bodies production against nuclear structures (Bolouri et al.,2022), SLE affecting mainly woemn of childbearing age and is chracterized by unpredictable flares and remissions , disease variety varied from mild episode disorder to arpidly progressive life -threatening illness.. LN is diagnosed by either the presence of proteinuria \>0.5g/day. active urinary sediment , or an unexplained rise in serum creatinine there fore , identifying new invasive biomarkers of LN severity and outcome is mandatory, Renal Arterial resistive index ( RRI) is anon invasive biomarker that has been studied as apotential indicator of disease activity in LN patients.

CONDITIONS

Official Title

Renal Arterial Resistive Index as a Noninvasive Biomarker of Disease Activity in Lupus Nephritis Patients

Who Can Participate

Age: 18Years - 50Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Aged 18 years or older
  • Diagnosed with Systemic Lupus Erythematosus (SLE) meeting SLICC classification criteria
  • Able to cooperate and answer questions
  • Able and willing to provide written informed consent
Not Eligible

You will not qualify if you...

  • Having other autoimmune diseases
  • Diabetes
  • Hypertension
  • Heart failure
  • Liver diseases
  • Chronic renal failure
  • Renal artery stenosis
  • Renal vein thrombosis
  • Intrarenal arteriovenous fistula
  • Obstructive nephropathy
  • Urinary tract obstruction affecting renal artery resistive index
  • Unable to cooperate
  • Unable or unwilling to provide written informed consent

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Sohag university Hospital

Sohag, Egypt, Sohag

Actively Recruiting

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Research Team

D

Doaa R Abdelkarim, resident

CONTACT

E

Esam M Abualfadl, professor

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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Renal Arterial Resistive Index as a Noninvasive Biomarker of Disease Activity in Lupus Nephritis Patients | DecenTrialz