Actively Recruiting
Renal Biopsies in Post-liver Transplantation Patients With Renal Impairment
Led by RenJi Hospital · Updated on 2025-11-28
369
Participants Needed
2
Research Sites
447 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Investigators will conduct this single-center, prospective cohort study to explore the prevalence and risk factors of renal function progression in post-liver transplantation patients with renal impairment after renal biospy and to understand the the pathology of kidney disease in post-liver transplantation patients with renal impairment.
CONDITIONS
Official Title
Renal Biopsies in Post-liver Transplantation Patients With Renal Impairment
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 18 and 75 years
- Patients who have received a liver transplant
- New onset proteinuria (24-hour proteinuria >1g/24h or urinary albumin creatinine ratio >300mg/g on at least two occasions), and/or renal impairment: eGFR <60 mL/min/1.73 m² on at least two occasions, and/or serum creatinine increase ≥50% from baseline
- Have received renal biopsy within the past 3 months
- Signed informed consent form
You will not qualify if you...
- Patients who have received a kidney transplant
- Hepatic failure
- Severe bleeding risk or platelet count <70×10⁹/L
- Chronic kidney insufficiency with eGFR <30 mL/min/1.73 m², kidney atrophy, solitary kidney, medullary sponge kidney, polycystic kidney, or obstructive nephropathy
- Uncontrolled mental disease or inability to cooperate during biopsy
- Pregnancy or lactation
- Considered unsuitable for the study by investigators
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine
Shanghai, China, 200127
Not Yet Recruiting
2
Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine
Shanghai, China, 200127
Actively Recruiting
Research Team
S
Shan Mou, Dr
CONTACT
H
Haijiao Jin, Dr
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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