Actively Recruiting

Age: 18Years +
All Genders
NCT05060783

Renal Cancer Detection With Liquid Biopsy

Led by Zealand University Hospital · Updated on 2024-01-30

200

Participants Needed

1

Research Sites

313 weeks

Total Duration

On this page

Sponsors

Z

Zealand University Hospital

Lead Sponsor

L

Lund University

Collaborating Sponsor

AI-Summary

What this Trial Is About

Glycosaminoglycans (GAGs) were significantly altered in localized as well advanced RCC compared to healthy samples. In addition, GAG scores correlated with progression-free survival and overall survival (OS) in a prospective cohort of patients with metastatic ccRCC and localized RCC. However, it is still unknown whether alterations in plasma and urine GAGs are exquisitely specific to RCC or are shared by other benign lesions in the kidney, such as angiomyolipomas, oncocytomas, or PEComa.

CONDITIONS

Official Title

Renal Cancer Detection With Liquid Biopsy

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients with CT scan suspicion of renal tumor showing no signs of renal cancer
  • Histological confirmation of clear cell renal cell carcinoma or oncocytoma by biopsy or surgical specimen
  • Signed informed consent
  • Ability to undergo study procedures
Not Eligible

You will not qualify if you...

  • Non-clear cell renal cell carcinoma
  • Renal cell carcinoma with pure sarcomatoid differentiation (kidney sarcoma)
  • Use of heparin for active diseases requiring blood thinning such as deep vein thrombosis or lung embolism (heparin use for thrombus prevention within 4 weeks after primary surgery is allowed)

AI-Screening

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Trial Site Locations

Total: 1 location

1

Zealand University Hospital

Roskilde, Denmark, 4000

Actively Recruiting

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How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

3

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