Actively Recruiting
Renal Denervation in Patients With Chronic Heart Failure With Preserved Ejection Fraction
Led by Xinjiang Medical University · Updated on 2024-02-01
200
Participants Needed
1
Research Sites
156 weeks
Total Duration
On this page
Sponsors
X
Xinjiang Medical University
Lead Sponsor
F
First Affiliated Hospital of Xinjiang Medical University
Collaborating Sponsor
AI-Summary
What this Trial Is About
This study aims to explore the potential of RDN as a therapy for HFpEF in a Prospective, Multicenter, Randomized, Blinded, Sham-controlled Study.
CONDITIONS
Official Title
Renal Denervation in Patients With Chronic Heart Failure With Preserved Ejection Fraction
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Signs or symptoms of heart failure
- Normal or mildly abnormal systolic left ventricular function (LVEF ≥ 50%)
- Evidence of diastolic left ventricular dysfunction
- Diagnosis of hypertension per WHO criteria, treated with at least two antihypertensive drugs for at least 6 months, with blood pressure controlled below 140/90 mmHg by 24-hour ambulatory measurement
- Stable heart failure medication regimen with no changes for at least 2 weeks prior to enrollment, expected to continue for at least 6 months
You will not qualify if you...
- Known secondary cause of hypertension
- Anatomy not suitable for renal denervation
- Systolic heart failure with LVEF below 50%
- Estimated glomerular filtration rate (eGFR) below 30 mL/min/1.73m2
- Serious medical conditions that may affect safety or effectiveness, including clinically significant peripheral vascular disease, abdominal aortic aneurysm, bleeding disorders, significant anemia, or arrhythmias such as atrial fibrillation
- Pregnancy, nursing, or planning to become pregnant
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
The First Affiliated Hospital of Xinjiang Medical University
Ürümqi, Xinjiang, China, 830000
Actively Recruiting
Research Team
X
Xiang Xie
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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