Actively Recruiting
Renal and Hepatic Abnormal Doppler Patterns in Trauma
Led by Azienda Usl di Bologna · Updated on 2026-03-25
350
Participants Needed
1
Research Sites
226 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this observational study is to learn about renal and hepatic blood flow abnormalities detected by bedside ultrasound in adult patients admitted to the intensive care unit (ICU) following major trauma. The main questions it aims to answer are: * How reliably can trained operators measure renal Doppler and venous congestion scores (RDRI and VExUS) across different hospitals? * How common are abnormal kidney and liver blood flow patterns in major trauma patients during the first 72 hours of ICU admission? * Are these abnormal patterns associated with acute kidney injury or the need for mechanical ventilation? Participants admitted to ICUs or high-dependency units (HDUs) with major trauma (Injury Severity Score \>15) will undergo non-invasive bedside ultrasound assessments at admission and at 24, 48, and 72 hours. No additional treatments or interventions will be given as part of this study. Kidney function will also be checked at 6 months after hospital discharge.
CONDITIONS
Official Title
Renal and Hepatic Abnormal Doppler Patterns in Trauma
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18-65 years
- Admission within 24 hours from traumatic injury
- Injury Severity Score (ISS) greater than 15
You will not qualify if you...
- Age less than 18 or greater than 65 years
- Known heart failure classified as New York Heart Association (NYHA) class II or higher
- Chronic kidney disease of any stage or chronic renal replacement therapy
- Chronic respiratory disease requiring home oxygen or ventilation
- Radiological evidence of vascular or parenchymal renal injury on trauma CT preventing reliable Doppler assessment
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Ospedale Maggiore C.A. Pizzardi AUSL Bologna
Bologna, Italy
Actively Recruiting
Research Team
F
Federico Moro, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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