Renal and Hepatic Abnormal Doppler Patterns in Trauma: a Multicentre Prospective Observational Study

What this Trial Is About

Researchers are investigating abnormalities in kidney and liver blood flow detected by bedside ultrasound in adults admitted to intensive care units (ICUs) after major trauma. This observational study aims to understand how reliably trained operators can measure renal Doppler and venous congestion scores across different hospitals, how common abnormal blood flow patterns are during the first 72 hours of ICU admission, and whether these abnormalities relate to acute kidney injury or the need for mechanical ventilation. Participants will have non-invasive bedside ultrasound assessments, including renal Doppler and Venous Excess Ultrasound (VExUS) scores, performed at admission (within 6 hours) and again at 24, 48, and 72 hours after ICU admission. No additional treatments will be given as part of the study. Kidney function will also be checked six months after hospital discharge to assess long-term outcomes. During the study, participants' kidney and liver blood flow patterns will be monitored through ultrasound at multiple time points. Researchers will evaluate acute kidney injury severity using established criteria up to seven days after ICU admission, as well as ventilator-free days within 30 days of enrollment. Long-term kidney function will be assessed approximately six months post-discharge. The total participation includes initial ICU monitoring and follow-up kidney function evaluation months later.

Renal and Hepatic Abnormal Doppler Patterns in Trauma