Actively Recruiting

Age: 18Years +
All Genders
NCT05728957

Renal Mass Biopsy, PEER, and 99mTc-sestamibi SPECT/CT for Patients With Clinically Localized Renal Tumors

Led by Loyola University · Updated on 2025-03-19

100

Participants Needed

1

Research Sites

565 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The goal of this clinical trial is to better tell apart whether kidney tumors are benign (not cancer) or malignant (cancer) based on a biopsy or imaging tests and ask patients how they feel about decisions they make about treatment of their kidney tumor. The main objectives are: To estimate and compare the diagnostic accuracy of renal mass biopsy alone, PEER (with renal mass biopsy), and 99mTc-sestamibi SPECT/CT (with renal mass biopsy for hot tumors) to differentiate malignant and benign renal tumors. To estimate and compare the diagnostic accuracy of renal mass biopsy, PEER (with renal mass biopsy), and 99mTc-sestamibi SPECT/CT (with renal mass biopsy for hot tumors) to differentiate oncocytoma from chromophobe RCC. Participants will be asked to complete survey questions related to their health and kidney tumor at the start and end of the study. These can be done on paper, electronically, or by telephone.

CONDITIONS

Official Title

Renal Mass Biopsy, PEER, and 99mTc-sestamibi SPECT/CT for Patients With Clinically Localized Renal Tumors

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosed with a clinically localized renal tumor 7 cm or smaller with a solid component suspicious for cancer based on imaging
  • Have CT images of the tumor with and without contrast within the past year or planned CT scan
  • At least 18 years old
  • Eligible or planned for partial or radical nephrectomy as decided by primary urologist
  • Eligible or planned for renal mass biopsy as decided by primary urologist
  • Estimated kidney function (glomerular filtration rate) of 30 ml/min/1.73 m2 or higher
Not Eligible

You will not qualify if you...

  • Pregnant as determined by local radiology policy
  • Evidence of cancer spread to lymph nodes or distant sites
  • History of other cancers with concern for kidney metastasis
  • Known allergy to technetium or sestamibi

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Loyola University Medical Center

Maywood, Illinois, United States, 60153

Actively Recruiting

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Research Team

G

Gopal N Gupta, MD

CONTACT

A

Agnes Natonton

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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Renal Mass Biopsy, PEER, and 99mTc-sestamibi SPECT/CT for Patients With Clinically Localized Renal Tumors | DecenTrialz