Actively Recruiting
Renal Perfusion and the Development of AKI Following Traumatic Injury
Led by King's College Hospital NHS Trust · Updated on 2025-04-08
20
Participants Needed
1
Research Sites
115 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Acute kidney injury (AKI) is a complication of traumatic haemorrhagic shock (THS) and together these conditions increase mortality risk. Although septic shock patients who develop severe AKI are known to develop hypoperfusion of the renal cortex, little is known regarding intra-renal perfusion changes in THS. The aim of the current study is to investigate the effects of THS on renal microcirculatory perfusion.
CONDITIONS
Official Title
Renal Perfusion and the Development of AKI Following Traumatic Injury
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age > 18 years
- Within 24 hours of ICU admission following traumatic injury
- Received any blood products during initial resuscitation
- Lactate > 2 mmol/l at any stage prior to study enrolment
You will not qualify if you...
- Known intolerance to Sonovue or any other ultrasound contrast agent
- Patients with un-survivable injuries or not expected to survive 24 hours with palliative intent
- Known chronic kidney disease stage 4 or end stage renal failure
- Pregnancy
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
King's College Hospital
London, United Kingdom, SE5 9RS
Actively Recruiting
Research Team
S
Sam Hutchings
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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