Repeatability and Reproducibility of ADC Maps in Head and Neck Cancer Using Standardized DWI A Prospective Multicenter Observational Study

What this Trial Is About

Researchers are studying the consistency and reliability of ADC maps in imaging for patients with head and neck cancer, specifically focusing on squamous cell carcinomas (SCC) of the hypopharynx, oropharynx, or oral cavity. This study evaluates both primary tumors and lymph node lesions using a standardized diffusion-weighted imaging (DWI) protocol to improve diagnostic imaging techniques. The imaging uses a spin-echo echo-planar sequence (SE-EPI) performed on 1.5 T or 3 T MRI scanners, depending on the equipment available at each participating center. These images are acquired after administering any required contrast medium, following a standard protocol designed to ensure uniform data collection across multiple centers. Participants will undergo DWI scans where researchers will assess the repeatability of ADC maps in both primary and nodal lesions over an 18-month period. The main measurement is how consistent these imaging results are over time, helping to improve the reliability of cancer imaging. The study also monitors for image quality and any artifacts that may affect analysis.

Repeatability and Reproducibility of the ADC Map in Head and Neck Cancer. Prospective Multicenter Study