Actively Recruiting
Repeated CBD Administration and Cannabis Outcomes
Led by Hannah Harris · Updated on 2026-05-05
23
Participants Needed
1
Research Sites
191 weeks
Total Duration
On this page
Sponsors
H
Hannah Harris
Lead Sponsor
N
National Institute on Drug Abuse (NIDA)
Collaborating Sponsor
AI-Summary
What this Trial Is About
This outpatient study examines how cannabidiol (CBD) affects the behavioral and pain-relieving effects of cannabis.
CONDITIONS
Official Title
Repeated CBD Administration and Cannabis Outcomes
Who Can Participate
Eligibility Criteria
You may qualify if you...
- English-speaking, literate adults
- Male or female
- Between the ages of 18 and 55
- Body Mass Index from 18.5 to 32.0 kg/m2
- Not currently seeking treatment for cannabis or drug use
- Able to provide written informed consent and perform all study procedures
- If female, a negative pregnancy test and use of effective contraception during study participation
- Negative urine drug test for drugs of abuse (other than cannabis) prior to every laboratory session
- Otherwise healthy as determined by medical history, physical exam, vital signs, and laboratory tests
You will not qualify if you...
- Physiologic drug dependence on opioids, benzodiazepines, barbiturates, or alcohol requiring medical management
- Clinically significant acute or chronic medical problems requiring daily medication or ongoing care
- Current or past major psychiatric disorder limiting study participation
- Use of cannabis only for medical reasons with no recreational use
- Unrelenting chronic pain preventing participation (unable to sit for 8 hours)
- Current use of daily prescription medications that could interfere with the study, including certain enzyme inducers
- Clinically significant abnormal ECG or laboratory findings
- History of seizure disorder
- Significant history of head injuries requiring medical management or with lasting effects
- Self-report of synthetic cannabis use in the past 30 days
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of Kentucky
Lexington, Kentucky, United States, 40508
Actively Recruiting
Research Team
P
Paul A Nuzzo, M.A.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
BASIC_SCIENCE
Number of Arms
6
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