Actively Recruiting
Repetitive Transcranial Magnetic Stimulation, a Form of Non-invasive Brain Stimulation, as a Possible Treatment for Post-stroke Fatigue.
Led by VA Office of Research and Development · Updated on 2026-04-21
60
Participants Needed
1
Research Sites
237 weeks
Total Duration
On this page
Sponsors
V
VA Office of Research and Development
Lead Sponsor
J
Joseph Maxwell Cleland VA Medical Center
Collaborating Sponsor
AI-Summary
What this Trial Is About
This experimental trial is investigating the use of magnetic stimulation of the brain as a possible treatment for post-stroke fatigue in people who have had a stroke more than six months prior to enrolling. Fatigue is a common condition after a stroke and can negatively impact an individual's ability to perform desired social and physical activities. Magnetic stimulation of the brain has been shown to improve signs and symptoms of related psychological (e.g., depression) conditions. Participants in this trial will receive a type of magnetic stimulation called repetitive transcranial magnetic stimulation, or rTMS. The investigators will measure feelings of fatigue and other clinical characteristics related to mood and cognition before and after participants receive rTMS.
CONDITIONS
Official Title
Repetitive Transcranial Magnetic Stimulation, a Form of Non-invasive Brain Stimulation, as a Possible Treatment for Post-stroke Fatigue.
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 34 and 80 years
- More than 6 months since stroke
- Clinically present fatigue
You will not qualify if you...
- Contraindications to MRI, TMS, or rTMS such as implanted metal in the head or history of seizures
- Unable to follow simple three-step instructions
- Diagnosed comorbid neurological conditions like multiple sclerosis, Parkinson's disease, or moderate/severe traumatic brain injury
- Pregnancy
- Stroke affecting stimulation sites
- Severe hypertension with resting systolic blood pressure over 200 or diastolic blood pressure over 120
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Atlanta VA Medical and Rehab Center, Decatur, GA
Decatur, Georgia, United States, 30033-4004
Actively Recruiting
Research Team
J
John H Kindred
CONTACT
C
Christina Young
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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