Actively Recruiting
Repetitive Transcranial Magnetic Stimulation for Post-concussion Headaches
Led by State University of New York - Upstate Medical University · Updated on 2025-10-10
60
Participants Needed
1
Research Sites
208 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study aims to examine the long-term effect of repetitive transcranial magnetic stimulation (rTMS), a non-invasive brain stimulation technique, on chronic headaches following mild traumatic brain injury (mTBI). rTMS has been shown to be effective in reducing chronic headaches without side effects commonly seen in medications, such as sleepiness and addiction. This study uses rTMS to manage chronic headaches to improve post-concussion symptoms and reduce the economic burden due to delayed recovery. This project aims to better identify biomarkers for diagnosis and prognosis and maximize recovery from mTBI.
CONDITIONS
Official Title
Repetitive Transcranial Magnetic Stimulation for Post-concussion Headaches
Who Can Participate
Eligibility Criteria
You may qualify if you...
- 18 to 55 years old
- Mild traumatic brain injury with loss of consciousness less than 30 minutes, Glasgow Coma Scale between 13 and 15, or post-traumatic amnesia of 24 hours or less
- Diagnosis of persistent post-traumatic headache per International Classification of Headache Disorders, 3rd edition (ICHD-3)
- Headache started within 7 days after head trauma
- Headache persists for 3 months or more after head trauma despite standard care
- Average headache intensity 3 or higher on a numerical rating scale at least 3 days per week
- No signs of radiculopathy or peripheral neuropathy on electromyography or clinical evaluation
- No evidence of other possible headache causes
You will not qualify if you...
- History of chronic headache diagnoses such as migraine, tension, or cluster headaches prior to mild traumatic brain injury
- History of other neurological conditions treated with medications that affect the central nervous system
- Contraindications for receiving transcranial magnetic stimulation, including history of epileptic seizures or implants like cardiac pacemakers or intracerebral vascular clips
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
SUNY Upstate Medical University
Syracuse, New York, United States, 13210
Actively Recruiting
Research Team
Y
Yi-Ling Kuo, PT, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
4
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