Actively Recruiting
Replacing Bone Marrow Diagnostics With Peripheral Blood Analysis in Cytopenia Patients
Led by Weizmann Institute of Science · Updated on 2026-03-25
1500
Participants Needed
2
Research Sites
182 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This observational, multi-center study aims to collect data in order to develop a novel, minimally invasive diagnostic tool for MDS based on peripheral blood profiling of circulating hematopoietic stem and progenitor cells (cHSPCs) using single-cell RNA sequencing and DNA sequencing.
CONDITIONS
Official Title
Replacing Bone Marrow Diagnostics With Peripheral Blood Analysis in Cytopenia Patients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients aged 18 years and older with suspected or confirmed MDS referred for bone marrow evaluation for diagnosis or risk assessment due to cytopenia
- Platelet count less than 150 x 10^9/L
- Absolute neutrophil count less than 1.8 x 10^9/L
- Hemoglobin less than 13 g/dL for males and less than 12 g/dL for females
- No evidence of iron, folinic acid, or B12 deficiency in both sexes
You will not qualify if you...
- Women who are pregnant
- Previous diagnosis of leukemia including AML, MPN, ALL, CLL, MGUS/MM, or any other gammopathy
- Lymphocyte count greater than 5000/μL
- Patients currently on disease-related therapy except treatment with erythropoietin or prednisone
- Patients who have undergone a bone marrow transplant
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
University of California San Diego
San Diego, California, United States, 92093
Actively Recruiting
2
University of Miami
Miami, Florida, United States, 33146
Actively Recruiting
Research Team
C
Clinical Trial Manage
CONTACT
L
Liran Shlush, Prof.
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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