RENAL AID A Data and Tissue Repository Studying Autoimmune, Inflammatory, and Diabetic Kidney Diseases Including Biopsy and Transplant Cases to Understand Disease Progression and Treatment

What this Trial Is About

Researchers are collecting data from a large group of people with various kidney diseases, including those related to diabetes, autoimmune conditions, inflammation, and kidney transplants. The study aims to create a combined data and tissue repository called RENAL AID, which links clinical, laboratory, genetic, and imaging information to better understand factors that predict disease progression, therapy response, and kidney biopsy results. The goal is to find non-invasive markers that can help diagnose kidney problems without the need for biopsy in the future. This research includes three groups one with patients undergoing kidney biopsy where tissue is stored and followed every 3 months for the first year, then yearly a second group of patients who had biopsies without stored tissue or have diabetic kidney disease without biopsy, followed annually and a third group of kidney transplant patients needing biopsy for monitoring or clinical reasons, assessed at biopsy time. Blood, urine, and serum samples are collected at visits for research purposes. Control subjects without kidney disease can also be included with data and specimen storage. Participants will provide informed consent and undergo regular evaluations including collection of blood, urine, and serum samples. Researchers will monitor changes in disease progression for up to 10 years. The data collected will include demographic, clinical, histological, genetic, and imaging information. This long-term observational study allows comparisons across different kidney disease states and control subjects to discover new predictive markers and disease mechanisms.

Repository of Novel Analytes Leading to Autoimmune, Inflammatory and Diabetic Nephropathies (RENAL AID)