Actively Recruiting
Repurposing Atovaquone for the Treatment of Platinum-Resistant Ovarian Cancer
Led by Emory University · Updated on 2025-09-11
28
Participants Needed
1
Research Sites
189 weeks
Total Duration
On this page
Sponsors
E
Emory University
Lead Sponsor
N
National Cancer Institute (NCI)
Collaborating Sponsor
AI-Summary
What this Trial Is About
This phase II trial test tests how well repurposing atovaquone works in treating patients with platinum-resistant ovarian cancer. Atovaquone is used for the treatment or prevention of certain infections. Atovaquone is in a class of medications called antiprotozoal agents. It works by stopping the growth of certain types of protozoa that can cause pneumonia. Giving atovaquone may be effective in treating platinum-resistant ovarian cancer and result in improved outcomes compared to standard chemotherapy regimens.
CONDITIONS
Official Title
Repurposing Atovaquone for the Treatment of Platinum-Resistant Ovarian Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients with platinum-resistant, high-grade serous ovarian cancer, defined as disease progression within six months of completion of their last platinum-based chemotherapy
- Eastern Cooperative Oncology Group (ECOG) performance status of 0 or 1
- No limit on the number of prior therapies
- Open to non-English speaking patients
- Open to patients referred from community practice
You will not qualify if you...
- Patients younger than 18 years old
- Pregnant or breastfeeding patients
- Patients who are incarcerated
- Patients unable to provide consent or lacking decision-making capacity
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Emory University Hospital/Winship Cancer Institute
Atlanta, Georgia, United States, 30322
Actively Recruiting
Research Team
N
Namita Khanna, MD, MSPH
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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