Study of Rescue Stenting After Mechanical Thrombectomy in Adults With Large Vessel Ischemic Stroke Treated Within 24 Hours

What this Trial Is About

This research investigates patients with acute large-vessel occlusion stroke LVOS who undergo mechanical thrombectomy and rescue stenting when initial treatments fail. The study aims to understand real-world antithrombotic strategies used in emergency stenting, particularly in those treated with intravenous thrombolysis IVT, and to assess the safety of stenting after IVT. It addresses challenges such as recanalization failure and the uncertain timing of antiplatelet therapy after IVT. The study follows patients undergoing rescue stenting within 24 hours of stroke onset after thrombectomy. Researchers observe the antithrombotic treatments chosen in these emergency cases, including the use of glycoprotein IIbIIIa receptor inhibitors and dual antiplatelet therapy. No experimental interventions are assigned, as this is an observational study assessing current practices across multiple centers. Participants will be monitored for safety, focusing on the rate of symptomatic cerebral hemorrhage within 24 hours post-treatment, and their functional outcome at 3 months using the modified Rankin Scale. The study collects data on treatments, complications, and recovery outcomes over time to better understand the effectiveness and risks of rescue stenting after IVT. The total duration of participation varies according to follow-up schedules.

Rescue Stenting and Intravenous Thrombolysis In Patients With Large Vessel Ischemic Stroke