Actively Recruiting
Research on the Application of 99mTc-TCR-FAPI SPECT Imaging in Rheumatoid Arthritis
Led by Luo Yaping · Updated on 2025-08-24
20
Participants Needed
1
Research Sites
154 weeks
Total Duration
On this page
Sponsors
L
Luo Yaping
Lead Sponsor
P
Peking Union Medical College Hospital
Collaborating Sponsor
AI-Summary
What this Trial Is About
This study proposes to evaluate 99mTc-CTR-FAPI SPECT imaging as a cost-effective, low-radiation, and widely accessible alternative to 68Ga-FAPI PET/CT for assessing synovial lesions in RA patients, aiming to validate its diagnostic consistency with both PET/CT and physical examinations while correlating imaging findings with clinical disease activity metrics to establish a practical tool for long-term RA monitoring.
CONDITIONS
Official Title
Research on the Application of 99mTc-TCR-FAPI SPECT Imaging in Rheumatoid Arthritis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 18 and 75 years old
- Meet the 2010 American College of Rheumatology/European Union for Rheumatology classification criteria for rheumatoid arthritis
- Have moderate to high disease activity based on clinical assessment (CDAI or SDAI score)
You will not qualify if you...
- Have other autoimmune diseases
- Have concurrent tumors
- Are pregnant, planning pregnancy, breastfeeding, or in the preconception period
- Are of childbearing age without effective contraception during the study
- Have active infections
- Experience claustrophobia or mental disorders that prevent cooperation
- Have any condition deemed inappropriate for participation by the researchers
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Peking Union Medical College Hospital
Beijing, Beijing Municipality, China, 100730
Actively Recruiting
Research Team
Y
Yaping Luo, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
DIAGNOSTIC
Number of Arms
1
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