Actively Recruiting
Research on the Brain Mechanism of taVNS in Regulating PD Motor Symptoms
Led by The First Affiliated Hospital with Nanjing Medical University · Updated on 2024-07-03
32
Participants Needed
1
Research Sites
16 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study is a double blind comparative study exploring the neural underpinnings of taVNS modulating PD motor deficits. We hypothesize that taVNS might improve PD motor deficits by regulating the balance between excitation and inhibition in the primary motor cortex.
CONDITIONS
Official Title
Research on the Brain Mechanism of taVNS in Regulating PD Motor Symptoms
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosed with idiopathic Parkinson Disease according to Movement Disorder Society Clinical Diagnostic Criteria
- Hoehn and Yahr stage 2 or less while ON medication
- Stable Parkinson Disease medication for at least one month before the study
- Aged between 40 and 80 years
- Able to provide written informed consent
- Able to cooperate with testing and taVNS treatment
You will not qualify if you...
- Cognitive impairment with Montreal Cognitive Assessment score below 24
- Severe tremor or levodopa-induced dyskinesia
- Taking anticholinergics or drugs affecting brain function
- Contraindications for taVNS treatment
- Received vagus nerve stimulation treatment within the past six months
- Severe neurological, kidney, heart, or liver disease
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
the First Affiliated Hospital of Nanjing Medical University
Nanjing, Jiangsu, China, 210029
Actively Recruiting
Research Team
Z
Zhang Kezhong
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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