Actively Recruiting
Research Into Diagnostic and Prognostic Molecular and Imaging Biomarkers of Ocular Disorders Associated With Neurovascular Deregulation: Biocor Cohort
Led by Clinact · Updated on 2024-06-20
400
Participants Needed
1
Research Sites
132 weeks
Total Duration
On this page
Sponsors
C
Clinact
Lead Sponsor
A
Association CRO - Tous unis pour la vision
Collaborating Sponsor
AI-Summary
What this Trial Is About
BIOCOR is an interventional clinical trial whose main objectives are Objectif are identify molecular biomarker(s) of ocular rosacea and pachychoroid. Endpoints are : Correlation between pachychoroidosis (defined by choroidal phenotype parameters in OCT and autofluorescence) or the stage of ocular rosacea (ROSCO(29) definition) and biological markers selected on the basis of preclinical work (animal model) and by unbiased methods (proteomics, metabolomics, meibum lipidomics). The study of circulating, ocular and functional biomarkers would enable us to confirm our hypothesis and identify patients who could benefit from treatments that regulate the ANS and/or mineralocorticoid pathways.
CONDITIONS
Official Title
Research Into Diagnostic and Prognostic Molecular and Imaging Biomarkers of Ocular Disorders Associated With Neurovascular Deregulation: Biocor Cohort
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Male or female over 18 years of age, of European origin, with signed genetic consent
- Clear ocular media suitable for OCT and autofluorescence imaging
- Signed consent form
- Affiliated to a health insurance scheme
- Control patients are those scheduled for cataract surgery or visual assessment
You will not qualify if you...
- High myopia greater than 6 diopters
- Diabetic retinopathy, hereditary retinal dystrophy, untreated retinal detachment, choroidal ocular tumor, or choroidal hemangioma
- Epithelial or stromal keratopathy other than ocular rosacea
- Corneal surgery less than 3 months old or keratoplasty
- Being deprived of liberty or under guardianship or curatorship
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Departement of Ophthalmology, COCHIN Hospital
Paris, France, 75679
Actively Recruiting
Research Team
C
CRA
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
DIAGNOSTIC
Number of Arms
3
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