Actively Recruiting

Phase Not Applicable
Age: 18Years - 75Years
All Genders
NCT07271576

Research on the Protective Effects of Phycocyanin Against Liver Fibrosis and Cirrhosis

Led by Second Affiliated Hospital, School of Medicine, Zhejiang University · Updated on 2025-12-09

10

Participants Needed

1

Research Sites

104 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This clinical trial aims to determine whether phycocyanin, a natural protein derived from spirulina, can help treat liver fibrosis or cirrhosis in adult patients. The main questions it aims to answer are: * Can phycocyanin reduce blood levels of liver enzymes (such as ALT and AST) that indicate liver damage? * Can phycocyanin improve liver stiffness as measured by ultrasound? Researchers will compare the phycocyanin intervention group with a control group that receives a placebo (a similar-looking maltodextrin supplement without active ingredients) to explore if phycocyanin is more effective in treating liver fibrosis/cirrhosis. Participants will: * Take one sachet of either phycocyanin or placebo daily for at least 4 weeks. * Attend regular clinic appointments (typically every 2-3 months) for routine monitoring of your liver condition, which will include blood and urine tests. * Provide blood and stool samples once before the treatment and once after the 4-week treatment period. * Undergo an ultrasound evaluation of liver stiffness. The study will last approximately 2 years, and the personal information of all patients will be kept strictly confidential.

CONDITIONS

Official Title

Research on the Protective Effects of Phycocyanin Against Liver Fibrosis and Cirrhosis

Who Can Participate

Age: 18Years - 75Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults between the ages of 18 and 75
  • Diagnosed with liver fibrosis or cirrhosis
  • Willing to participate and able to sign informed consent
  • No acute illness or worsening symptoms for at least 4 weeks before enrollment
Not Eligible

You will not qualify if you...

  • Presence of severe other health conditions
  • Allergy to phycocyanin
  • History of severe mental illness that may affect treatment compliance

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

The Second Affiliated Hospital of Zhejiang University

Hangzhou, China

Actively Recruiting

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Research Team

X

Xiaopeng Cai

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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Research on the Protective Effects of Phycocyanin Against Liver Fibrosis and Cirrhosis | DecenTrialz