Actively Recruiting
Research on the Protective Effects of Phycocyanin Against Liver Fibrosis and Cirrhosis
Led by Second Affiliated Hospital, School of Medicine, Zhejiang University · Updated on 2025-12-09
10
Participants Needed
1
Research Sites
104 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This clinical trial aims to determine whether phycocyanin, a natural protein derived from spirulina, can help treat liver fibrosis or cirrhosis in adult patients. The main questions it aims to answer are: * Can phycocyanin reduce blood levels of liver enzymes (such as ALT and AST) that indicate liver damage? * Can phycocyanin improve liver stiffness as measured by ultrasound? Researchers will compare the phycocyanin intervention group with a control group that receives a placebo (a similar-looking maltodextrin supplement without active ingredients) to explore if phycocyanin is more effective in treating liver fibrosis/cirrhosis. Participants will: * Take one sachet of either phycocyanin or placebo daily for at least 4 weeks. * Attend regular clinic appointments (typically every 2-3 months) for routine monitoring of your liver condition, which will include blood and urine tests. * Provide blood and stool samples once before the treatment and once after the 4-week treatment period. * Undergo an ultrasound evaluation of liver stiffness. The study will last approximately 2 years, and the personal information of all patients will be kept strictly confidential.
CONDITIONS
Official Title
Research on the Protective Effects of Phycocyanin Against Liver Fibrosis and Cirrhosis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults between the ages of 18 and 75
- Diagnosed with liver fibrosis or cirrhosis
- Willing to participate and able to sign informed consent
- No acute illness or worsening symptoms for at least 4 weeks before enrollment
You will not qualify if you...
- Presence of severe other health conditions
- Allergy to phycocyanin
- History of severe mental illness that may affect treatment compliance
AI-Screening
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Trial Site Locations
Total: 1 location
1
The Second Affiliated Hospital of Zhejiang University
Hangzhou, China
Actively Recruiting
Research Team
X
Xiaopeng Cai
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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