Actively Recruiting

Phase Not Applicable
Age: 18Years - 35Years
FEMALE
Healthy Volunteers
ID07209566

The Effect of Vaginal Somatovisceral Pain on Hip Extension Mobility and Strength in Women at Mid-cycle With Dysmenorrhea vs. Controls: A Case-control Study

Led by Azusa Pacific University · Updated on 2025-10-07

60

Participants Needed

1

Research Sites

30 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are studying women with dysmenorrhea, a condition involving painful periods, to see if they have a stronger musculoskeletal and autonomic nervous system response to painful internal stimuli compared to women without this pain. The study also aims to explore how interoceptive awareness, or the ability to sense internal body signals, might affect this relationship. This investigation seeks to better understand pain perception and related body changes in women with this condition. The study involves two groups: women with moderate to severe menstrual pain and age-matched controls with mild or no pain. Participants will attend two sessions: one for information and preparation, including tracking their menstrual cycle and heart rate variability (HRV) daily for 30 days, and a lab session where they will receive a controlled visceral pain stimulus. During the lab visit, hip mobility and muscle strength will be measured before and after the pain stimulus, and HRV will be recorded throughout. Participants will fill out questionnaires, perform daily HRV measurements with a phone app, and attend a lab session where detailed physical and physiological assessments occur. The study will measure changes in hip range of motion, muscle strength, and heart rate variability immediately after the pain stimulus. It will also assess interoceptive awareness during testing. The total participation includes daily monitoring for about a month and a single lab visit, with safety and comfort maintained throughout.

CONDITIONS

Brief Title

A Research Study Exploring How Musculoskeletal Function and the Autonomic Nervous System Relate to Visceral Pain in Women With and Without Dysmenorrhea (Painful Periods).

Who Can Participate

Age: 18Years - 35Years
FEMALE
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Non-pregnant women
  • Not taking hormonal birth control
  • Between 18 and 36 years old
  • Regular menstrual cycles
  • Able to track menstrual cycle and perform HRV measurements using apps
Not Eligible

You will not qualify if you...

  • Currently pregnant or breastfeeding
  • Given birth within the last six months
  • Undergoing in-vitro fertilization treatments
  • Had abdominal, lumbar, or pelvic surgery within the last 12 months
  • Suffer from chronic pain conditions
  • Have active genitourinary infection
  • Incontinent of bowel or bladder
  • Diagnosed with pelvic organ prolapse, severe labral pathology, femoral acetabular impingement, interstitial cystitis, endometriosis, pelvic inflammatory disease, irritable bowel syndrome, or other pelvic pathology
  • Cycle length less than 28 days or longer than 35 days
  • History of sexual assault
  • Anovulatory without hormonal birth control or amenorrheic

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

Monitoring

Duration - 30 days

Participants track their menstrual cycle and measure their heart rate variability daily using apps for 30 days starting from the first day of their period.

Daily measurements using apps

Diagnostic Evaluation

Duration - 1 day

Participants attend a lab session where baseline hip extension and heart rate variability are measured. A visceral pain stimulus is applied using a vaginal barostat probe, and hip mobility and dorsiflexor strength are assessed before and after the stimulus.

1 in-person lab session

Trial Site Locations

Total: 1 location

1

Azusa Pacific University

Azusa, California, United States, 91702

Actively Recruiting

Loading map...

Research Team

M

Megan M Steele, PT, DPT, PhD(c)

J

Jennifer Fernandez, PT, DPT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

PREVENTION

Number of Arms

1

Similar Trials

An Open-Label, Single-Group Study to Evaluate the Effect of ...

Uterine Fibroids

Actively Recruiting

1 location

Frequently Asked Questions

Have more questions? Get in touch with our team for quick support

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here

Published Research Related To This Trial

A noninvasive bladder sensory test supports a role for dysmenorrhea increasing bladder noxious mechanosensitivity.

Frank F Tu, Aliza E Epstein, Kristen E Pozolo...

https://pubmed.ncbi.nlm.nih.gov/23370073

Common and distinct neural representations of aversive somatic and visceral stimulation in healthy individuals.

Lukas Van Oudenhove, Philip A Kragel, Patrick Dupont...

https://pubmed.ncbi.nlm.nih.gov/33230131

Reliability of goniometric and trigonometric techniques for measuring hip-extension range of motion using the modified Thomas test.

C Brent Wakefield, Amanda Halls, Nicole Difilippo...

https://pubmed.ncbi.nlm.nih.gov/25562458