Actively Recruiting

Phase 3
Age: 12Years - 65Years
All Genders
NCT07060885

A Research Study of House Dust Mite (HDM) SLIT-tablet for the Treatment of HDM Allergy in Chinese Participants Aged 12-65

Led by ALK-Abelló A/S · Updated on 2025-12-31

300

Participants Needed

30

Research Sites

47 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

A research study of house dust mite (HDM) SLIT-tablet for the treatment of HDM allergy in Chinese participants aged 12-65.

CONDITIONS

Official Title

A Research Study of House Dust Mite (HDM) SLIT-tablet for the Treatment of HDM Allergy in Chinese Participants Aged 12-65

Who Can Participate

Age: 12Years - 65Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Male or female Chinese subjects aged 12-65 years
  • Clinical history of house dust mite allergic rhinitis/rhinoconjunctivitis, with or without asthma
  • Allergic rhinitis symptoms despite allergy treatment during the year before screening
  • Allergic rhinitis symptoms on at least 8 of the last 14 days of the baseline period
  • Use of symptom-relief medication for house dust mite allergic rhinitis on at least 8 of the last 14 days of the baseline period
  • Positive skin prick test and IgE for Dermatophagoides pteronyssinus or Dermatophagoides farinae at screening
  • Lung function at least 70% of predicted value
Not Eligible

You will not qualify if you...

  • Sensitization and regular exposure to perennial allergens
  • Nasal or pharyngeal conditions interfering with safety or efficacy evaluation
  • Asthma requiring treatment with high-dose inhaled corticosteroids
  • History of systemic allergic reaction

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 30 locations

1

Beijing Tongren Hospital, Capital Medical University

Beijing, Beijing Municipality, China, 100730

Actively Recruiting

2

Fujian Provincial Hospital

Fuzhou, Fujian, China, 350001

Actively Recruiting

3

The first hospital affiliated Fujian medical University

Fuzhou, Fujian, China, 350005

Actively Recruiting

4

The first affiliated hospital of guangzhou medical university-respiratory department

Guangzhou, Guangdong, China, 510120

Actively Recruiting

5

The Third Affiliated Hospital, Sun Yat-sen University

Guangzhou, Guangdong, China, 510630

Actively Recruiting

6

The Third Affilliated Hospital of Southern Medical University

Guangzhou, Guangdong, China, 510630

Actively Recruiting

7

Shenzhen Children's Hospital - Respiratory

Shenzhen, Guangdong, China, 518026

Actively Recruiting

8

Huazhong University of science and Technology Union Shenzhen Hospital(Nanshan Hospital) - Endocrinology

Shenzhen, Guangdong, China, 518052

Actively Recruiting

9

The Fifth Affiliated Hospital of Sun Yat-Sen University - University Hospital

Zhuhai, Guangdong, China, 510275

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10

The First Affiliated Hospital of Guangxi Medical University

Nanning, Guangxi, China, 530021

Actively Recruiting

11

The People's Hospital of Guangxi Zhuang Autonomous Region - Nephrology - Oncology

Nanning, Guangxi, China, 530021

Actively Recruiting

12

Hainan General Hospital - Respiratory

Haikou, Hainan, China, 570311

Actively Recruiting

13

The Third Hospital of Changsha - Pulmonology

Changshacun, Henan, China, 410015

Actively Recruiting

14

The First Affiliated Hospital of University of South China - Endocrinology

Hengyang, Henan, China, 421001

Actively Recruiting

15

Jingzhou Central Hospital - Otorhinolaryngology

Jingzhou, Hubei, China, 434020

Actively Recruiting

16

Union Hospital Tongji Medical College Huazhong University of Science and Technology - Oncology

Wuhan, Hubei, China, 430022

Actively Recruiting

17

Tongji Hospital affiliated to Tongji Medical College of Huazhong University of Science & Technology

Wuhan, Hubei, China, 430030

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18

Jiangsu Province Hospital/ The First Affiliated Hospital with Nanjing Medical University - Otorhinolaryngology

Nanjing, Jiangsu, China, 210029

Actively Recruiting

19

The First Affiliated Hospital of Soochow University - Respiratory

Suzhou, Jiangsu, China, 215006

Actively Recruiting

20

Nanchang University - The First Affiliated Hospital

Nanchang, Jiangxi, China, 330046

Actively Recruiting

21

The Second Affiliated Hospital of Nanchang University

Nanchang, Jiangxi, China, 330047

Actively Recruiting

22

The Second Affiliated Hospital of Xi an Jiaotong University (Xibei Hospital) - Nephrology

Xi'an, Shaanxi, China, 710004

Actively Recruiting

23

Shanghai Jiaotong University School of Medicine, Ruijin Hospital

Shanghai, Shanghai Municipality, China, 200025

Actively Recruiting

24

Zhongshan Hospital

Shanghai, Shanghai Municipality, China, 200032

Actively Recruiting

25

Peking Union Medical College Hospital

Beijing, Sichuan, China, 100730

Actively Recruiting

26

Sichuan University - West China Second University Hospital (WCSUH) (West China Women's and Children's Hospital)

Chengdu, Sichuan, China, 610017

Actively Recruiting

27

West China Hospital of Sichuan University - Otorhinolaryngology

Chengdu, Sichuan, China, 610041

Actively Recruiting

28

The First Affiliated Hospital of Chongqing Medical University - Respiratory

Chongqing, Sichuan, China, 400016

Actively Recruiting

29

Zhejiang provincial people's hospital

Hangzhou, Zhejiang, China, 310014

Actively Recruiting

30

The 2nd School of Medicine, WMU/The 2nd Affiliated Hospital and Yuying Children's Hospital of WMU - Pediatrics

Wenzhou, Zhejiang, China, 325027

Actively Recruiting

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Research Team

H

Head of Clinical Project Management

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

QUADRUPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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