Actively Recruiting
A Research Study Looking at How Different Doses of Study Medicine (Inno8) Work in the Body of People With Haemophilia A
Led by Novo Nordisk A/S · Updated on 2026-04-24
30
Participants Needed
33
Research Sites
67 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study will test how different doses of study medicine (Inno8) work in the bodies of people with haemophilia A. The purpose of the study is to see if Inno8 is safe to use for people with haemophilia A. The study medicine is a new medicine that cannot yet be prescribed by doctors. The study will last for about 11 weeks.
CONDITIONS
Official Title
A Research Study Looking at How Different Doses of Study Medicine (Inno8) Work in the Body of People With Haemophilia A
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Male
- Age 18-64 years (both inclusive) at the time of signing the informed consent
- Body weight greater than or equal to 45 kilograms
- Diagnosis of congenital haemophilia A with factor VIII activity less than or equal to 15% with or without factor VIII inhibitors, based on medical records
You will not qualify if you...
- Current or prior exposure to any prophylactic treatment for haemophilia A within 5 half-lives of the medicinal product by the time of screening
- Body mass index 30.0 kilogram per square meter or higher
- Increased risk of thrombosis, such as a known history of personal or first-degree relative(s) with unprovoked deep vein thrombosis
- Any clinical signs or established diagnosis of venous or arterial thromboembolic disease
- Any known coagulation disorders other than haemophilia A
- Ongoing or planned immune tolerance induction therapy
- Presence of clinically significant gastrointestinal disorders potentially affecting absorption of drugs and/or nutrients, as judged by the investigator
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 33 locations
1
UC Denver Hemoph & Thrombo Ctr
Aurora, Colorado, United States, 80045
Not Yet Recruiting
2
Indiana Hemophilia-Thromb Ctr
Indianapolis, Indiana, United States, 46260
Actively Recruiting
3
University of Iowa_Iowa City
Iowa City, Iowa, United States, 52242
Actively Recruiting
4
Penn State MS Hershey Med Ctr
Hershey, Pennsylvania, United States, 17033-2360
Actively Recruiting
5
St Christopher Hosp for Child
Philadelphia, Pennsylvania, United States, 19134
Not Yet Recruiting
6
Universitätsklinik für Innere Medizin V
Innsbruck, Austria, 6020
Actively Recruiting
7
AKH - Klin. Abt. f. Haematologie u. Haemostaseologie
Vienna, Austria, 1090
Actively Recruiting
8
Cliniques universitaires Saint-Luc
Brussels, Belgium, 1200
Not Yet Recruiting
9
HCL - HOPITAL LOUIS PRADEL - Unité d'hémostase Clinique
Bron, France, 69500
Not Yet Recruiting
10
Vivantes Netzwerk für Gesundheit GmbH - Vivantes Klinikum im Friedrichshain
Berlin, Germany, 10249
Actively Recruiting
11
Universitätsklinikum Bonn - Institut für Experimentelle Hämatologie
Bonn, Germany, 53127
Not Yet Recruiting
12
Medizinische Hochschule Hannover - Hämatologie, Hämostaseologie, Onkologie
Hanover, Germany, 30625
Actively Recruiting
13
AOU Careggi Firenze
Florence, Italy, 50134
Actively Recruiting
14
Azienda Ospedaliera Universitaria Federico II di Napoli
Naples, Italy, 80131
Actively Recruiting
15
Uniwersytecki Szpital Kliniczny w Bialymstoku
Bialystok, Poland, 15-276
Actively Recruiting
16
Uniwersyteckie Centrum Kliniczne
Gdansk, Poland, 80-214
Actively Recruiting
17
Samodzielny Publiczny Szpital Kliniczny im. Andrzeja Mielęckiego Slaskiego Uniwersytetu Medycznego w Katowicach
Katowice, Poland, 40-032
Not Yet Recruiting
18
Uniwersytecki Szpital Kliniczny nr 1 Klinika Hematoonkologii i Transplantacji Szpiku
Lublin, Poland, 20-081
Not Yet Recruiting
19
Uniwersytecki Szpital Kliniczny W Poznaniu
Poznan, Poland, 60-569
Not Yet Recruiting
20
Instytut Hematologii i Transfuzjologii
Warsaw, Poland, 02-776
Actively Recruiting
21
ULS De Santo António, E.P.E. _H.Santo António_ Imunohemoterapia
Porto, Portugal, 4050-342
Not Yet Recruiting
22
ULS São João, E.P.E._H.São João_Imunohemoterapia
Porto, Portugal, 4200-319
Not Yet Recruiting
23
Hospital Vall d'Hebron
Barcelona, Spain, 08035
Actively Recruiting
24
Hospital Universitario La Paz
Madrid, Spain, 28046
Actively Recruiting
25
Hospital Regional Universitario de Málaga
Málaga, Spain, 29010
Actively Recruiting
26
Hospital Clinico Universitario de Salamanca
Salamanca, Spain, 37007
Actively Recruiting
27
Hospital La Fe - Hemostasia y Trombosis
Valencia, Spain, 46026
Not Yet Recruiting
28
Skåne US - Koagulationsmottagning
Malmö, Sweden, 214 28
Not Yet Recruiting
29
KS Solna - Koagulationsmottagningen
Solna, Sweden, 171 64
Not Yet Recruiting
30
Zentrum für Labormedizin
Sankt Gallen, Switzerland, 9008
Not Yet Recruiting
31
Queen Elizabeth Hospital, Birmingham - Haemophilia
Birmingham, United Kingdom, B15 2TH
Not Yet Recruiting
32
Royal Free Hospital - Haemophilia
London, United Kingdom, NW3 2QG
Actively Recruiting
33
Royal Hallamshire Hospital
Sheffield, United Kingdom, S10 2JF
Not Yet Recruiting
Research Team
N
Novo Nordisk
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
3
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