Actively Recruiting

Phase 4
Age: 18Years +
FEMALE
NCT07157423

A Research Study to See How Safe is Eptacog Alfa When Used to Stop Heavy Bleeding in Women After Giving Birth in India

Led by Novo Nordisk A/S · Updated on 2026-03-27

64

Participants Needed

8

Research Sites

82 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study will look at how safe is the medicine eptacog alfa when used in women in India for stopping heavy bleeding after giving birth. If participants have heavy bleeding after giving birth then they will get the medicine eptacog alfa. This study will be conducted to get more knowledge on the safety of the medicine eptacog alfa use in these women. At first participants will receive one dose of medicine eptacog alfa. If the given dose is not helpful to stop the bleeding, participants will get one additional dose. The study will last for about 30-35 days.

CONDITIONS

Official Title

A Research Study to See How Safe is Eptacog Alfa When Used to Stop Heavy Bleeding in Women After Giving Birth in India

Who Can Participate

Age: 18Years +
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Provided informed consent before any study activities
  • Adult women aged 18 years or older
  • Delivered after 27 weeks of pregnancy
  • Diagnosed with severe postpartum haemorrhage not responding to uterotonics
Not Eligible

You will not qualify if you...

  • Previously participated in this study
  • Mental incapacity, unwillingness, or language barriers preventing understanding or cooperation
  • History of thromboembolism
  • History of bleeding disorders
  • History or presence of severe childbirth complications such as disseminated intravascular coagulation, HELLP syndrome, thrombotic thrombocytopenic purpura, or pre-eclampsia (apart from severe postpartum haemorrhage)
  • Underwent invasive obstetric procedures for current bleeding before enrollment (excluding uterine balloon tamponade and external aortic compression)
  • Any chronic or severe disease that might risk safety or compliance
  • Participation in any other interventional clinical study before screening

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 8 locations

1

KLE Belgum

Belagavi, Karnataka, India, 590010

Actively Recruiting

2

Calicut Medical College

Kozhikode, Kerala, India, 673008

Actively Recruiting

3

Calicut Medical College

Kozhikode, Kerala, India, 673008

Not Yet Recruiting

4

Seth GS Medical College & KEM Hospital

Mumbai, Maharashtra, India, 400012

Actively Recruiting

5

All India Institute of Medical Sciences_New Dehli

New Delhi, National Capital Territory of Delhi, India, 110029

Actively Recruiting

6

SMS Hospital

Jaipur, Rajasthan, India, 302004

Not Yet Recruiting

7

KLE Belgum

Belagavi, India, 590010

Not Yet Recruiting

8

Post Graduate Institute of Medical Education & Research_Chandigarh

Chandigarh, India, 160012

Not Yet Recruiting

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Research Team

N

Novo Nordisk

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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