Actively Recruiting
Research on the Use of Probiotics in the Prevention and Treatment of Inflammatory Bowel Disease
Led by Wecare Probiotics Co., Ltd. · Updated on 2025-04-04
50
Participants Needed
1
Research Sites
51 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This project involves the use of oral Lactobacillus reuteri as an adjunct therapy for 8 weeks. Endoscopic observation of intestinal inflammation will be conducted at 1 month, 3 months, 6 months, and 12 months after the administration of the drug. Intestinal fluid will be collected endoscopically for 16S RNA analysis to assess changes in the gut microbiota. Inflammatory changes in the patients will be detected through peripheral blood tests, and fecal calprotectin levels will be measured to evaluate the progression of the disease.
CONDITIONS
Official Title
Research on the Use of Probiotics in the Prevention and Treatment of Inflammatory Bowel Disease
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Be over 18 years old
- Agree to sign informed consent
- Have been diagnosed with IBD for at least 3 months but not more than 3 years
You will not qualify if you...
- Does not meet the diagnostic criteria of Crohn's Disease (CD)
- Have other autoimmune diseases, infectious diseases, or malignant tumors
- Are pregnant or lactating with CD
- Have serious diseases of the liver, kidney, heart, or lung
- Have allergic diseases such as asthma or allergic rhinitis
- Have mental illness or alcohol addiction
- Have suspected cancer in the intestines
- Have used antibiotics, probiotics, or prebiotics in the past three months
- Have had intestinal surgery (except appendicitis surgery)
- Currently have an infection
- Have had cancer in the last 5 years
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Gastroenterology Department of Jiangsu Province （Suqian）Hospital
Suqian, Jiangsu, China, 223800
Actively Recruiting
Research Team
H
Huanhuan Chen, Doctor
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
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